Simpson D - Search Results

1

A Multi-Omics Approach Identifies Key Regulatory Pathways Induced by Long-Term Zinc Supplementation in Human Primary Retinal Pigment Epithelium.

Emri E, Kortvely E, Dammeier S, Klose F, Simpson D, Consortium ER, Den Hollander AI, Ueffing M, Lengyel I. Emri E, et al. Among authors: simpson d. Nutrients. 2020 Oct 6;12(10):3051. doi: 10.3390/nu12103051. Nutrients. 2020. PMID: 33036197 Free PMC article.

2

Zinc Supplementation Induced Transcriptional Changes in Primary Human Retinal Pigment Epithelium: A Single-Cell RNA Sequencing Study to Understand Age-Related Macular Degeneration.

Emri E, Cappa O, Kelly C, Kortvely E, SanGiovanni JP, McKay BS, Bergen AA, Simpson DA, Lengyel I. Emri E, et al. Cells. 2023 Feb 28;12(5):773. doi: 10.3390/cells12050773. Cells. 2023. PMID: 36899910 Free PMC article.

3

Characterisation of the advanced glycation endproduct receptor complex in the retinal pigment epithelium.

McFarlane S, Glenn JV, Lichanska AM, Simpson DA, Stitt AW. McFarlane S, et al. Among authors: simpson da. Br J Ophthalmol. 2005 Jan;89(1):107-12. doi: 10.1136/bjo.2004.045914. Br J Ophthalmol. 2005. PMID: 15615757 Free PMC article.

4

Short and long-term effect of dexamethasone on the transcriptome profile of primary human trabecular meshwork cells in vitro.

Kathirvel K, Lester K, Haribalaganesh R, Krishnadas R, Muthukkaruppan V, Lane B, Simpson DA, Goljanek-Whysall K, Sheridan C, Bharanidharan D, Willoughby CE, Senthilkumari S. Kathirvel K, et al. Among authors: simpson da. Sci Rep. 2022 May 18;12(1):8299. doi: 10.1038/s41598-022-12443-7. Sci Rep. 2022. PMID: 35585182 Free PMC article.

5

Single-cell transcriptomic profiling provides insights into retinal endothelial barrier properties.

Watson MI, Barabas P, McGahon M, McMahon M, Fuchs MA, Curtis TM, Simpson DA. Watson MI, et al. Mol Vis. 2020 Nov 27;26:766-779. eCollection 2020. Mol Vis. 2020. PMID: 33380778 Free PMC article.

6

Genome-Wide RNA Sequencing of Human Trabecular Meshwork Cells Treated with TGF-β1: Relevance to Pseudoexfoliation Glaucoma.

Roodnat AW, Callaghan B, Doyle C, Henry M, Goljanek-Whysall K, Simpson DA, Sheridan C, Atkinson SD, Willoughby CE. Roodnat AW, et al. Among authors: simpson da. Biomolecules. 2022 Nov 15;12(11):1693. doi: 10.3390/biom12111693. Biomolecules. 2022. PMID: 36421707 Free PMC article.

7

A novel diagnostic test detects a low frequency of the hemicentin Gln5345Arg variant among Northern Irish age related macular degeneration patients.

McKay GJ, Clarke S, Hughes A, McConnell V, Schultz DW, Klein ML, Silvestri G, Simpson DA. McKay GJ, et al. Mol Vis. 2004 Sep 24;10:682-7. Mol Vis. 2004. PMID: 15467524 Free article.

8

Advanced glycation end product (AGE) accumulation on Bruch's membrane: links to age-related RPE dysfunction.

Glenn JV, Mahaffy H, Wu K, Smith G, Nagai R, Simpson DA, Boulton ME, Stitt AW. Glenn JV, et al. Invest Ophthalmol Vis Sci. 2009 Jan;50(1):441-51. doi: 10.1167/iovs.08-1724. Epub 2008 Aug 1. Invest Ophthalmol Vis Sci. 2009. PMID: 18676633

9

Genome-wide transcriptome profiling of human trabecular meshwork cells treated with TGF-β2.

Callaghan B, Lester K, Lane B, Fan X, Goljanek-Whysall K, Simpson DA, Sheridan C, Willoughby CE. Callaghan B, et al. Sci Rep. 2022 Jun 10;12(1):9564. doi: 10.1038/s41598-022-13573-8. Sci Rep. 2022. PMID: 35689009 Free PMC article.

10

Preparation of planar retinal specimens: verification by histology, mRNA profiling, and proteome analysis.

McKay GJ, Campbell L, Oliver M, Brockbank S, Simpson DA, Curry WJ. McKay GJ, et al. Mol Vis. 2004 Mar 29;10:240-7. Mol Vis. 2004. PMID: 15064678 Free article.

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