Simorini F - Search Results

1

Novel, highly potent aldose reductase inhibitors: cyano(2-oxo-2,3-dihydroindol-3-yl)acetic acid derivatives.

Da Settimo F, Primofiore G, Da Settimo A, La Motta C, Simorini F, Novellino E, Greco G, Lavecchia A, Boldrini E. Da Settimo F, et al. Among authors: simorini f. J Med Chem. 2003 Apr 10;46(8):1419-28. doi: 10.1021/jm030762f. J Med Chem. 2003. PMID: 12672241

2

Dialkylaminoalkylindolonaphthyridines as potential antitumour agents: synthesis, cytotoxicity and DNA binding properties.

Dalla Via L, Gia O, Marciani Magno S, Da Settimo A, Primofiore G, Da Settimo F, Simorini F, Marini AM. Dalla Via L, et al. Among authors: simorini f. Eur J Med Chem. 2002 Jun;37(6):475-86. doi: 10.1016/s0223-5234(02)01372-7. Eur J Med Chem. 2002. PMID: 12204474

3

N,N-dialkyl-2-phenylindol-3-ylglyoxylamides. A new class of potent and selective ligands at the peripheral benzodiazepine receptor.

Primofiore G, Da Settimo F, Taliani S, Simorini F, Patrizi MP, Novellino E, Greco G, Abignente E, Costa B, Chelli B, Martini C. Primofiore G, et al. Among authors: simorini f. J Med Chem. 2004 Mar 25;47(7):1852-5. doi: 10.1021/jm030973k. J Med Chem. 2004. PMID: 15027878 Free article.

4

Novel, highly potent adenosine deaminase inhibitors containing the pyrazolo[3,4-d]pyrimidine ring system. Synthesis, structure-activity relationships, and molecular modeling studies.

Da Settimo F, Primofiore G, La Motta C, Taliani S, Simorini F, Marini AM, Mugnaini L, Lavecchia A, Novellino E, Tuscano D, Martini C. Da Settimo F, et al. Among authors: simorini f. J Med Chem. 2005 Aug 11;48(16):5162-74. doi: 10.1021/jm050136d. J Med Chem. 2005. PMID: 16078836

5

Naphtho[1,2-d]isothiazole acetic acid derivatives as a novel class of selective aldose reductase inhibitors.

Da Settimo F, Primofiore G, La Motta C, Sartini S, Taliani S, Simorini F, Marini AM, Lavecchia A, Novellino E, Boldrini E. Da Settimo F, et al. Among authors: simorini f. J Med Chem. 2005 Nov 3;48(22):6897-907. doi: 10.1021/jm050382p. J Med Chem. 2005. PMID: 16250648

6

Refinement of the benzodiazepine receptor site topology by structure-activity relationships of new N-(heteroarylmethyl)indol-3-ylglyoxylamides.

Primofiore G, Da Settimo F, Marini AM, Taliani S, La Motta C, Simorini F, Novellino E, Greco G, Cosimelli B, Ehlardo M, Sala A, Besnard F, Montali M, Martini C. Primofiore G, et al. Among authors: simorini f. J Med Chem. 2006 Apr 20;49(8):2489-95. doi: 10.1021/jm0511841. J Med Chem. 2006. PMID: 16610792

7

New fluorescent 2-phenylindolglyoxylamide derivatives as probes targeting the peripheral-type benzodiazepine receptor: design, synthesis, and biological evaluation.

Taliani S, Simorini F, Sergianni V, La Motta C, Da Settimo F, Cosimelli B, Abignente E, Greco G, Novellino E, Rossi L, Gremigni V, Spinetti F, Chelli B, Martini C. Taliani S, et al. Among authors: simorini f. J Med Chem. 2007 Jan 25;50(2):404-7. doi: 10.1021/jm061137o. J Med Chem. 2007. PMID: 17228885

8

Novel N-substituted indol-3-ylglyoxylamides probing the LDi and L1/L2 lipophilic regions of the benzodiazepine receptor site in search for subtype-selective ligands.

Primofiore G, Taliani S, Da Settimo F, Marini AM, La Motta C, Simorini F, Patrizi MP, Sergianni V, Novellino E, Greco G, Cosimelli B, Calderone V, Montali M, Besnard F, Martini C. Primofiore G, et al. Among authors: simorini f. J Med Chem. 2007 Apr 5;50(7):1627-34. doi: 10.1021/jm0607707. Epub 2007 Mar 3. J Med Chem. 2007. PMID: 17335185

9

Pyrido[1,2-a]pyrimidin-4-one derivatives as a novel class of selective aldose reductase inhibitors exhibiting antioxidant activity.

La Motta C, Sartini S, Mugnaini L, Simorini F, Taliani S, Salerno S, Marini AM, Da Settimo F, Lavecchia A, Novellino E, Cantore M, Failli P, Ciuffi M. La Motta C, et al. Among authors: simorini f. J Med Chem. 2007 Oct 4;50(20):4917-27. doi: 10.1021/jm070398a. Epub 2007 Sep 11. J Med Chem. 2007. PMID: 17845019

10

5-amino-2-phenyl[1,2,3]triazolo[1,2-a][1,2,4]benzotriazin-1-one: a versatile scaffold to obtain potent and selective A3 adenosine receptor antagonists.

Da Settimo F, Primofiore G, Taliani S, Marini AM, La Motta C, Simorini F, Salerno S, Sergianni V, Tuccinardi T, Martinelli A, Cosimelli B, Greco G, Novellino E, Ciampi O, Trincavelli ML, Martini C. Da Settimo F, et al. Among authors: simorini f. J Med Chem. 2007 Nov 15;50(23):5676-84. doi: 10.1021/jm0708376. Epub 2007 Oct 10. J Med Chem. 2007. PMID: 17927167

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