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Pretreatment of Glioblastoma with Bortezomib Potentiates Natural Killer Cell Cytotoxicity through TRAIL/DR5 Mediated Apoptosis and Prolongs Animal Survival.
Gras Navarro A, Espedal H, Joseph JV, Trachsel-Moncho L, Bahador M, Gjertsen BT, Kristoffersen EK, Simonsen A, Miletic H, Enger PØ, Rahman MA, Chekenya M. Gras Navarro A, et al. Among authors: simonsen a. Cancers (Basel). 2019 Jul 17;11(7):996. doi: 10.3390/cancers11070996. Cancers (Basel). 2019. PMID: 31319548 Free PMC article.
Bortezomib administered prior to temozolomide depletes MGMT, chemosensitizes glioblastoma with unmethylated MGMT promoter and prolongs animal survival.
Rahman MA, Gras Navarro A, Brekke J, Engelsen A, Bindesbøll C, Sarowar S, Bahador M, Bifulco E, Goplen D, Waha A, Lie SA, Gjertsen BT, Selheim F, Enger PØ, Simonsen A, Chekenya M. Rahman MA, et al. Among authors: simonsen a. Br J Cancer. 2019 Oct;121(7):545-555. doi: 10.1038/s41416-019-0551-1. Epub 2019 Aug 15. Br J Cancer. 2019. PMID: 31413318 Free PMC article.
AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells.
Lotsberg ML, Wnuk-Lipinska K, Terry S, Tan TZ, Lu N, Trachsel-Moncho L, Røsland GV, Siraji MI, Hellesøy M, Rayford A, Jacobsen K, Ditzel HJ, Vintermyr OK, Bivona TG, Minna J, Brekken RA, Baguley B, Micklem D, Akslen LA, Gausdal G, Simonsen A, Thiery JP, Chouaib S, Lorens JB, Engelsen AST. Lotsberg ML, et al. Among authors: simonsen a. J Thorac Oncol. 2020 Jun;15(6):973-999. doi: 10.1016/j.jtho.2020.01.015. Epub 2020 Feb 1. J Thorac Oncol. 2020. PMID: 32018052 Free PMC article.
GAK and PRKCD are positive regulators of PRKN-independent mitophagy.
Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Schultz SW, Aman Y, Lystad AH, Singh S, Singh S, Wesche J, Fang EF, Simonsen A. Munson MJ, et al. Among authors: simonsen a. Nat Commun. 2021 Oct 20;12(1):6101. doi: 10.1038/s41467-021-26331-7. Nat Commun. 2021. PMID: 34671015 Free PMC article.
GAK and PRKCD kinases regulate basal mitophagy.
Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Simonsen A. Munson MJ, et al. Among authors: simonsen a. Autophagy. 2022 Feb;18(2):467-469. doi: 10.1080/15548627.2021.2015154. Epub 2022 Jan 9. Autophagy. 2022. PMID: 35001811 Free PMC article.
Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide.
Johannessen TC, Hasan-Olive MM, Zhu H, Denisova O, Grudic A, Latif MA, Saed H, Varughese JK, Røsland GV, Yang N, Sundstrøm T, Nordal A, Tronstad KJ, Wang J, Lund-Johansen M, Simonsen A, Janji B, Westermarck J, Bjerkvig R, Prestegarden L. Johannessen TC, et al. Among authors: simonsen a. Int J Cancer. 2019 Apr 1;144(7):1735-1745. doi: 10.1002/ijc.31912. Epub 2018 Dec 11. Int J Cancer. 2019. PMID: 30289977 Free article.
440 results