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ProNGF, sortilin, and age-related neurodegeneration.
Al-Shawi R, Hafner A, Chun S, Raza S, Crutcher K, Thrasivoulou C, Simons P, Cowen T. Al-Shawi R, et al. Among authors: simons p. Ann N Y Acad Sci. 2007 Nov;1119:208-15. doi: 10.1196/annals.1404.024. Ann N Y Acad Sci. 2007. PMID: 18056969 Review.
Notch controls embryonic Schwann cell differentiation, postnatal myelination and adult plasticity.
Woodhoo A, Alonso MB, Droggiti A, Turmaine M, D'Antonio M, Parkinson DB, Wilton DK, Al-Shawi R, Simons P, Shen J, Guillemot F, Radtke F, Meijer D, Feltri ML, Wrabetz L, Mirsky R, Jessen KR. Woodhoo A, et al. Among authors: simons p. Nat Neurosci. 2009 Jul;12(7):839-47. doi: 10.1038/nn.2323. Epub 2009 Jun 14. Nat Neurosci. 2009. PMID: 19525946 Free PMC article.
A role for APP in Wnt signalling links synapse loss with β-amyloid production.
Elliott C, Rojo AI, Ribe E, Broadstock M, Xia W, Morin P, Semenov M, Baillie G, Cuadrado A, Al-Shawi R, Ballard CG, Simons P, Killick R. Elliott C, et al. Among authors: simons p. Transl Psychiatry. 2018 Sep 20;8(1):179. doi: 10.1038/s41398-018-0231-6. Transl Psychiatry. 2018. PMID: 30232325 Free PMC article.
Amyloid β synaptotoxicity is Wnt-PCP dependent and blocked by fasudil.
Sellers KJ, Elliott C, Jackson J, Ghosh A, Ribe E, Rojo AI, Jarosz-Griffiths HH, Watson IA, Xia W, Semenov M, Morin P, Hooper NM, Porter R, Preston J, Al-Shawi R, Baillie G, Lovestone S, Cuadrado A, Harte M, Simons P, Srivastava DP, Killick R. Sellers KJ, et al. Among authors: simons p. Alzheimers Dement. 2018 Mar;14(3):306-317. doi: 10.1016/j.jalz.2017.09.008. Epub 2017 Oct 19. Alzheimers Dement. 2018. PMID: 29055813 Free PMC article.
309 results