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Cell type- and brain region-resolved mouse brain proteome.
Sharma K, Schmitt S, Bergner CG, Tyanova S, Kannaiyan N, Manrique-Hoyos N, Kongi K, Cantuti L, Hanisch UK, Philips MA, Rossner MJ, Mann M, Simons M. Sharma K, et al. Among authors: simons m. Nat Neurosci. 2015 Dec;18(12):1819-31. doi: 10.1038/nn.4160. Epub 2015 Nov 2. Nat Neurosci. 2015. PMID: 26523646 Free PMC article.
Defective cholesterol clearance limits remyelination in the aged central nervous system.
Cantuti-Castelvetri L, Fitzner D, Bosch-Queralt M, Weil MT, Su M, Sen P, Ruhwedel T, Mitkovski M, Trendelenburg G, Lütjohann D, Möbius W, Simons M. Cantuti-Castelvetri L, et al. Among authors: simons m. Science. 2018 Feb 9;359(6376):684-688. doi: 10.1126/science.aan4183. Epub 2018 Jan 4. Science. 2018. PMID: 29301957
Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region.
Schlepckow K, Monroe KM, Kleinberger G, Cantuti-Castelvetri L, Parhizkar S, Xia D, Willem M, Werner G, Pettkus N, Brunner B, Sülzen A, Nuscher B, Hampel H, Xiang X, Feederle R, Tahirovic S, Park JI, Prorok R, Mahon C, Liang CC, Shi J, Kim DJ, Sabelström H, Huang F, Di Paolo G, Simons M, Lewcock JW, Haass C. Schlepckow K, et al. Among authors: simons m. EMBO Mol Med. 2020 Apr 7;12(4):e11227. doi: 10.15252/emmm.201911227. Epub 2020 Mar 10. EMBO Mol Med. 2020. PMID: 32154671 Free PMC article.
Oligodendrocytes Provide Antioxidant Defense Function for Neurons by Secreting Ferritin Heavy Chain.
Mukherjee C, Kling T, Russo B, Miebach K, Kess E, Schifferer M, Pedro LD, Weikert U, Fard MK, Kannaiyan N, Rossner M, Aicher ML, Goebbels S, Nave KA, Krämer-Albers EM, Schneider A, Simons M. Mukherjee C, et al. Among authors: simons m. Cell Metab. 2020 Aug 4;32(2):259-272.e10. doi: 10.1016/j.cmet.2020.05.019. Epub 2020 Jun 11. Cell Metab. 2020. PMID: 32531201 Free PMC article.
Cell-Type- and Brain-Region-Resolved Mouse Brain Lipidome.
Fitzner D, Bader JM, Penkert H, Bergner CG, Su M, Weil MT, Surma MA, Mann M, Klose C, Simons M. Fitzner D, et al. Among authors: simons m. Cell Rep. 2020 Sep 15;32(11):108132. doi: 10.1016/j.celrep.2020.108132. Cell Rep. 2020. PMID: 32937123 Free article.
Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia.
Colombo A, Dinkel L, Müller SA, Sebastian Monasor L, Schifferer M, Cantuti-Castelvetri L, König J, Vidatic L, Bremova-Ertl T, Lieberman AP, Hecimovic S, Simons M, Lichtenthaler SF, Strupp M, Schneider SA, Tahirovic S. Colombo A, et al. Among authors: simons m. Nat Commun. 2021 Feb 24;12(1):1158. doi: 10.1038/s41467-021-21428-5. Nat Commun. 2021. PMID: 33627648 Free PMC article.
1,483 results