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GDF11 Implications in Cancer Biology and Metabolism. Facts and Controversies.
Simoni-Nieves A, Gerardo-Ramírez M, Pedraza-Vázquez G, Chávez-Rodríguez L, Bucio L, Souza V, Miranda-Labra RU, Gomez-Quiroz LE, Gutiérrez-Ruiz MC. Simoni-Nieves A, et al. Front Oncol. 2019 Oct 15;9:1039. doi: 10.3389/fonc.2019.01039. eCollection 2019. Front Oncol. 2019. PMID: 31681577 Free PMC article. Review.
GDF11 exhibits tumor suppressive properties in hepatocellular carcinoma cells by restricting clonal expansion and invasion.
Gerardo-Ramírez M, Lazzarini-Lechuga R, Hernández-Rizo S, Jiménez-Salazar JE, Simoni-Nieves A, García-Ruiz C, Fernández-Checa JC, Marquardt JU, Coulouarn C, Gutiérrez-Ruiz MC, Pérez-Aguilar B, Gomez-Quiroz LE. Gerardo-Ramírez M, et al. Biochim Biophys Acta Mol Basis Dis. 2019 Jun 1;1865(6):1540-1554. doi: 10.1016/j.bbadis.2019.03.003. Epub 2019 Mar 16. Biochim Biophys Acta Mol Basis Dis. 2019. PMID: 30890427 Free article.
GDF11 restricts aberrant lipogenesis and changes in mitochondrial structure and function in human hepatocellular carcinoma cells.
Hernandez S, Simoni-Nieves A, Gerardo-Ramírez M, Torres S, Fucho R, Gonzalez J, Castellanos-Tapia L, Hernández-Pando R, Tejero-Barrera E, Bucio L, Souza V, Miranda-Labra R, Fernández-Checa JC, Marquardt JU, Gomez-Quiroz LE, García-Ruiz C, Gutiérrez-Ruiz MC. Hernandez S, et al. Among authors: simoni nieves a. J Cell Physiol. 2021 May;236(5):4076-4090. doi: 10.1002/jcp.30151. Epub 2020 Nov 10. J Cell Physiol. 2021. PMID: 33174245 Free article.
The Consumption of Cholesterol-Enriched Diets Conditions the Development of a Subtype of HCC with High Aggressiveness and Poor Prognosis.
Simoni-Nieves A, Salas-Silva S, Chávez-Rodríguez L, Escobedo-Calvario A, Desoteux M, Bucio L, Souza V, Miranda-Labra RU, Muñoz-Espinosa LE, Coulouarn C, Gutiérrez-Ruiz MC, Marquardt JU, Gomez-Quiroz LE. Simoni-Nieves A, et al. Cancers (Basel). 2021 Apr 6;13(7):1721. doi: 10.3390/cancers13071721. Cancers (Basel). 2021. PMID: 33917315 Free PMC article.
Cholesterol overload in the liver aggravates oxidative stress-mediated DNA damage and accelerates hepatocarcinogenesis.
Enríquez-Cortina C, Bello-Monroy O, Rosales-Cruz P, Souza V, Miranda RU, Toledo-Pérez R, Luna-López A, Simoni-Nieves A, Hernández-Pando R, Gutiérrez-Ruiz MC, Calvisi DF, Marquardt JU, Bucio L, Gomez-Quiroz LE. Enríquez-Cortina C, et al. Oncotarget. 2017 Oct 24;8(61):104136-104148. doi: 10.18632/oncotarget.22024. eCollection 2017 Nov 28. Oncotarget. 2017. PMID: 29262627 Free PMC article.
HGF induces protective effects in α-naphthylisothiocyanate-induced intrahepatic cholestasis by counteracting oxidative stress.
Salas-Silva S, Simoni-Nieves A, Razori MV, López-Ramirez J, Barrera-Chimal J, Lazzarini R, Bello O, Souza V, Miranda-Labra RU, Gutiérrez-Ruiz MC, Gomez-Quiroz LE, Roma MG, Bucio-Ortiz L. Salas-Silva S, et al. Biochem Pharmacol. 2020 Apr;174:113812. doi: 10.1016/j.bcp.2020.113812. Epub 2020 Jan 16. Biochem Pharmacol. 2020. PMID: 31954718
Relevance of Membrane Contact Sites in Cancer Progression.
Gil-Hernández A, Arroyo-Campuzano M, Simoni-Nieves A, Zazueta C, Gomez-Quiroz LE, Silva-Palacios A. Gil-Hernández A, et al. Among authors: simoni nieves a. Front Cell Dev Biol. 2021 Jan 12;8:622215. doi: 10.3389/fcell.2020.622215. eCollection 2020. Front Cell Dev Biol. 2021. PMID: 33511135 Free PMC article. Review.
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