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Targeted therapy against chemoresistant colorectal cancers: Inhibition of p38α modulates the effect of cisplatin in vitro and in vivo through the tumor suppressor FoxO3A.
Germani A, Matrone A, Grossi V, Peserico A, Sanese P, Liuzzi M, Palermo R, Murzilli S, Campese AF, Ingravallo G, Canettieri G, Tezil T, Simone C. Germani A, et al. Among authors: simone c. Cancer Lett. 2014 Mar 1;344(1):110-118. doi: 10.1016/j.canlet.2013.10.035. Epub 2013 Nov 9. Cancer Lett. 2014. PMID: 24215867
A SMYD3 Small-Molecule Inhibitor Impairing Cancer Cell Growth.
Peserico A, Germani A, Sanese P, Barbosa AJ, Di Virgilio V, Fittipaldi R, Fabini E, Bertucci C, Varchi G, Moyer MP, Caretti G, Del Rio A, Simone C. Peserico A, et al. Among authors: simone c. J Cell Physiol. 2015 Oct;230(10):2447-2460. doi: 10.1002/jcp.24975. J Cell Physiol. 2015. PMID: 25728514 Free PMC article.
Loss of STK11 expression is an early event in prostate carcinogenesis and predicts therapeutic response to targeted therapy against MAPK/p38.
Grossi V, Lucarelli G, Forte G, Peserico A, Matrone A, Germani A, Rutigliano M, Stella A, Bagnulo R, Loconte D, Galleggiante V, Sanguedolce F, Cagiano S, Bufo P, Trabucco S, Maiorano E, Ditonno P, Battaglia M, Resta N, Simone C. Grossi V, et al. Among authors: simone c. Autophagy. 2015 Nov 2;11(11):2102-2113. doi: 10.1080/15548627.2015.1091910. Autophagy. 2015. PMID: 26391455 Free PMC article.
Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy.
Celestini V, Tezil T, Russo L, Fasano C, Sanese P, Forte G, Peserico A, Lepore Signorile M, Longo G, De Rasmo D, Signorile A, Gadaleta RM, Scialpi N, Terao M, Garattini E, Cocco T, Villani G, Moschetta A, Grossi V, Simone C. Celestini V, et al. Among authors: simone c. Cell Death Dis. 2018 Feb 14;9(2):231. doi: 10.1038/s41419-018-0336-0. Cell Death Dis. 2018. PMID: 29445193 Free PMC article.
In vitro efficacy of ARQ 092, an allosteric AKT inhibitor, on primary fibroblast cells derived from patients with PIK3CA-related overgrowth spectrum (PROS).
Ranieri C, Di Tommaso S, Loconte DC, Grossi V, Sanese P, Bagnulo R, Susca FC, Forte G, Peserico A, De Luisi A, Bartuli A, Selicorni A, Melis D, Lerone M, Praticò AD, Abbadessa G, Yu Y, Schwartz B, Ruggieri M, Simone C, Resta N. Ranieri C, et al. Among authors: simone c. Neurogenetics. 2018 May;19(2):77-91. doi: 10.1007/s10048-018-0540-1. Epub 2018 Mar 16. Neurogenetics. 2018. PMID: 29549527 Free PMC article.
1,360 results