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An empirical pipeline for personalized diagnosis of Lafora disease mutations.
iScience. 2021 Oct 13;24(11):103276. doi: 10.1016/j.isci.2021.103276. eCollection 2021 Nov 19.
iScience. 2021.
PMID: 34755096
Free PMC article.
Targeting Pathogenic Lafora Bodies in Lafora Disease Using an Antibody-Enzyme Fusion.
Brewer MK, Uittenbogaard A, Austin GL, Segvich DM, DePaoli-Roach A, Roach PJ, McCarthy JJ, Simmons ZR, Brandon JA, Zhou Z, Zeller J, Young LEA, Sun RC, Pauly JR, Aziz NM, Hodges BL, McKnight TR, Armstrong DD, Gentry MS.
Brewer MK, et al. Among authors: simmons zr.
Cell Metab. 2019 Oct 1;30(4):689-705.e6. doi: 10.1016/j.cmet.2019.07.002. Epub 2019 Jul 25.
Cell Metab. 2019.
PMID: 31353261
Free PMC article.
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Generation and characterization of a laforin nanobody inhibitor.
Simmons ZR, Sharma S, Wayne J, Li S, Vander Kooi CW, Gentry MS.
Simmons ZR, et al.
Clin Biochem. 2021 Jul;93:80-89. doi: 10.1016/j.clinbiochem.2021.03.017. Epub 2021 Apr 5.
Clin Biochem. 2021.
PMID: 33831386
Free PMC article.
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Central Nervous System Delivery and Biodistribution Analysis of an Antibody-Enzyme Fusion for the Treatment of Lafora Disease.
Austin GL, Simmons ZR, Klier JE, Rondon A, Hodges BL, Shaffer R, Aziz NM, McKnight TR, Pauly JR, Armstrong DD, Vander Kooi CW, Gentry MS.
Austin GL, et al. Among authors: simmons zr.
Mol Pharm. 2019 Sep 3;16(9):3791-3801. doi: 10.1021/acs.molpharmaceut.9b00396. Epub 2019 Aug 2.
Mol Pharm. 2019.
PMID: 31329461
Free PMC article.
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