Simmons NL - Search Results

1

Marinopyrrole derivatives with sulfide spacers as selective disruptors of Mcl-1 binding to pro-apoptotic protein Bim.

Cheng C, Liu Y, Balasis ME, Garner TP, Li J, Simmons NL, Berndt N, Song H, Pan L, Qin Y, Nicolaou KC, Gavathiotis E, Sebti SM, Li R. Cheng C, et al. Among authors: simmons nl. Mar Drugs. 2014 Jul 29;12(8):4311-25. doi: 10.3390/md12084311. Mar Drugs. 2014. PMID: 25076060 Free PMC article.

2

Cyclic marinopyrrole derivatives as disruptors of Mcl-1 and Bcl-x(L) binding to Bim.

Cheng C, Liu Y, Balasis ME, Simmons NL, Li J, Song H, Pan L, Qin Y, Nicolaou KC, Sebti SM, Li R. Cheng C, et al. Among authors: simmons nl. Mar Drugs. 2014 Mar 7;12(3):1335-48. doi: 10.3390/md12031335. Mar Drugs. 2014. PMID: 24608970 Free PMC article.

3

Total synthesis and biological evaluation of marinopyrrole A and analogues.

Nicolaou KC, Simmons NL, Chen JS, Haste NM, Nizet V. Nicolaou KC, et al. Among authors: simmons nl. Tetrahedron Lett. 2011 Apr 27;52(17):2041-2043. doi: 10.1016/j.tetlet.2010.09.059. Tetrahedron Lett. 2011. PMID: 21499535 Free PMC article.

4

Enantioselective dichlorination of allylic alcohols.

Nicolaou KC, Simmons NL, Ying Y, Heretsch PM, Chen JS. Nicolaou KC, et al. Among authors: simmons nl. J Am Chem Soc. 2011 Jun 1;133(21):8134-7. doi: 10.1021/ja202555m. Epub 2011 May 10. J Am Chem Soc. 2011. PMID: 21542622 Free PMC article.

5

Synthesis and antioxidant evaluation of (S,S)- and (R,R)-secoisolariciresinol diglucosides (SDGs).

Mishra OP, Simmons N, Tyagi S, Pietrofesa R, Shuvaev VV, Valiulin RA, Heretsch P, Nicolaou KC, Christofidou-Solomidou M. Mishra OP, et al. Bioorg Med Chem Lett. 2013 Oct 1;23(19):5325-8. doi: 10.1016/j.bmcl.2013.07.062. Epub 2013 Aug 2. Bioorg Med Chem Lett. 2013. PMID: 23978651 Free PMC article.

6

Facile Access to Sterically Hindered Aryl Ketones via Carbonylative Cross-Coupling: Application to the Total Synthesis of Luteolin.

O'Keefe BM, Simmons N, Martin SF. O'Keefe BM, et al. Tetrahedron. 2011 Jun 17;67(24):4344-4351. doi: 10.1016/j.tet.2011.03.074. Tetrahedron. 2011. PMID: 21712966 Free PMC article.

7

Discovery of potent BET bromodomain 1 stereoselective inhibitors using DNA-encoded chemical library selections.

Modukuri RK, Yu Z, Tan Z, Ta HM, Ucisik MN, Jin Z, Anglin JL, Sharma KL, Nyshadham P, Li F, Riehle K, Faver JC, Duong K, Nagarajan S, Simmons N, Palmer SS, Teng M, Young DW, Yi JS, Kim C, Matzuk MM. Modukuri RK, et al. Proc Natl Acad Sci U S A. 2022 May 31;119(22):e2122506119. doi: 10.1073/pnas.2122506119. Epub 2022 May 27. Proc Natl Acad Sci U S A. 2022. PMID: 35622893 Free PMC article.

8

Carbonylative cross-coupling of ortho-disubstituted aryl iodides. convenient synthesis of sterically hindered aryl ketones.

O'Keefe BM, Simmons N, Martin SF. O'Keefe BM, et al. Org Lett. 2008 Nov 20;10(22):5301-4. doi: 10.1021/ol802202j. Epub 2008 Oct 24. Org Lett. 2008. PMID: 18947231 Free PMC article.

9

Palladium-Catalyzed Hydroxycarbonylation of (Hetero)aryl Halides for DNA-Encoded Chemical Library Synthesis.

Li JY, Miklossy G, Modukuri RK, Bohren KM, Yu Z, Palaniappan M, Faver JC, Riehle K, Matzuk MM, Simmons N. Li JY, et al. Bioconjug Chem. 2019 Aug 21;30(8):2209-2215. doi: 10.1021/acs.bioconjchem.9b00447. Epub 2019 Jul 31. Bioconjug Chem. 2019. PMID: 31329429 Free PMC article.

10

Identifying Oxacillinase-48 Carbapenemase Inhibitors Using DNA-Encoded Chemical Libraries.

Taylor DM, Anglin J, Park S, Ucisik MN, Faver JC, Simmons N, Jin Z, Palaniappan M, Nyshadham P, Li F, Campbell J, Hu L, Sankaran B, Prasad BVV, Huang H, Matzuk MM, Palzkill T. Taylor DM, et al. ACS Infect Dis. 2020 May 8;6(5):1214-1227. doi: 10.1021/acsinfecdis.0c00015. Epub 2020 Mar 25. ACS Infect Dis. 2020. PMID: 32182432 Free PMC article.

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