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Page 1
Cixutumumab reveals a critical role for IGF-1 in adipose and hepatic tissue remodelling during the development of diet-induced obesity.
Imrie H, Viswambharan H, Haywood NJ, Bridge KI, Yuldasheva NY, Galloway S, Simmons KJ, Cubbon RM, Sukumar P, Watt NT, Lichtenstein L, Wyatt JI, Kudo H, Goldin R, Rode B, Wheatcroft SB, Kearney MT. Imrie H, et al. Among authors: simmons kj. Adipocyte. 2022 Dec;11(1):366-378. doi: 10.1080/21623945.2022.2089394. Adipocyte. 2022. PMID: 35734881 Free PMC article.
Divergent effects of genetic and pharmacological inhibition of Nox2 NADPH oxidase on insulin resistance-related vascular damage.
Maqbool A, Watt NT, Haywood N, Viswambharan H, Skromna A, Makava N, Visnagri A, Shawer HM, Bridge K, Muminov SK, Griffin K, Beech DJ, Wheatcroft SB, Porter KE, Simmons KJ, Sukumar P, Shah AM, Cubbon RM, Kearney MT, Yuldasheva NY. Maqbool A, et al. Among authors: simmons kj. Am J Physiol Cell Physiol. 2020 Jul 1;319(1):C64-C74. doi: 10.1152/ajpcell.00389.2019. Epub 2020 May 13. Am J Physiol Cell Physiol. 2020. PMID: 32401607 Free PMC article.
Novel Paracrine Action of Endothelium Enhances Glucose Uptake in Muscle and Fat.
Viswambharan H, Yuldasheva NY, Imrie H, Bridge K, Haywood NJ, Skromna A, Hemmings KE, Clark ER, Gatenby VK, Cordell P, Simmons KJ, Makava N, Abudushalamu Y, Endesh N, Brown J, Walker AMN, Futers ST, Porter KE, Cubbon RM, Naseem K, Shah AM, Beech DJ, Wheatcroft SB, Kearney MT, Sukumar P. Viswambharan H, et al. Among authors: simmons kj. Circ Res. 2021 Sep 17;129(7):720-734. doi: 10.1161/CIRCRESAHA.121.319517. Epub 2021 Aug 21. Circ Res. 2021. PMID: 34420367 Free PMC article.
Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot, and reduce bleeding complications.
Kearney KJ, Pechlivani N, King R, Tiede C, Phoenix F, Cheah R, Macrae FL, Simmons KJ, Manfield IW, Smith KA, Spurgeon BEJ, Naseem KM, Ariens RAS, McPherson MJ, Tomlinson DC, Ajjan RA. Kearney KJ, et al. Among authors: simmons kj. Blood. 2019 Mar 14;133(11):1233-1244. doi: 10.1182/blood-2018-06-856195. Epub 2018 Dec 13. Blood. 2019. PMID: 30545831 Free PMC article.
Computational methods to identify new antibacterial targets.
McPhillie MJ, Cain RM, Narramore S, Fishwick CW, Simmons KJ. McPhillie MJ, et al. Among authors: simmons kj. Chem Biol Drug Des. 2015 Jan;85(1):22-9. doi: 10.1111/cbdd.12385. Chem Biol Drug Des. 2015. PMID: 24974974
Structure-based discovery of antibacterial drugs.
Simmons KJ, Chopra I, Fishwick CW. Simmons KJ, et al. Nat Rev Microbiol. 2010 Jul;8(7):501-10. doi: 10.1038/nrmicro2349. Nat Rev Microbiol. 2010. PMID: 20551974 Review.
55 results