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Iron Prevents Hypoxia-Associated Inflammation Through the Regulation of Nuclear Factor-κB in the Intestinal Epithelium.
Simmen S, Cosin-Roger J, Melhem H, Maliachovas N, Maane M, Baebler K, Weder B, Maeyashiki C, Spanaus K, Scharl M, de Vallière C, Zeitz J, Vavricka SR, Hausmann M, Rogler G, Ruiz PA. Simmen S, et al. Cell Mol Gastroenterol Hepatol. 2019;7(2):339-355. doi: 10.1016/j.jcmgh.2018.10.006. Epub 2018 Oct 17. Cell Mol Gastroenterol Hepatol. 2019. PMID: 30704983 Free PMC article. Clinical Trial.
Hypoxia Positively Regulates the Expression of pH-Sensing G-Protein-Coupled Receptor OGR1 (GPR68).
de Vallière C, Cosin-Roger J, Simmen S, Atrott K, Melhem H, Zeitz J, Madanchi M, Tcymbarevich I, Fried M, Kullak-Ublick GA, Vavricka SR, Misselwitz B, Seuwen K, Wagner CA, Eloranta JJ, Rogler G, Ruiz PA. de Vallière C, et al. Among authors: simmen s. Cell Mol Gastroenterol Hepatol. 2016 Jun 25;2(6):796-810. doi: 10.1016/j.jcmgh.2016.06.003. eCollection 2016 Nov. Cell Mol Gastroenterol Hepatol. 2016. PMID: 28174749 Free PMC article.
Hypoxia Reduces the Transcription of Fibrotic Markers in the Intestinal Mucosa.
Simmen S, Maane M, Rogler S, Baebler K, Lang S, Cosin-Roger J, Atrott K, Frey-Wagner I, Spielmann P, Wenger RH, Weder B, Zeitz J, Vavricka SR, Rogler G, de Vallière C, Hausmann M, Ruiz PA. Simmen S, et al. Inflamm Intest Dis. 2021 May;6(2):87-100. doi: 10.1159/000513061. Epub 2021 Mar 29. Inflamm Intest Dis. 2021. PMID: 34124180 Free PMC article.