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Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation.
Nat Commun. 2017 Jul 24;8(1):98. doi: 10.1038/s41467-017-00213-3.
Nat Commun. 2017.
PMID: 28740109
Free PMC article.
Iron Prevents Hypoxia-Associated Inflammation Through the Regulation of Nuclear Factor-κB in the Intestinal Epithelium.
Simmen S, Cosin-Roger J, Melhem H, Maliachovas N, Maane M, Baebler K, Weder B, Maeyashiki C, Spanaus K, Scharl M, de Vallière C, Zeitz J, Vavricka SR, Hausmann M, Rogler G, Ruiz PA.
Simmen S, et al.
Cell Mol Gastroenterol Hepatol. 2019;7(2):339-355. doi: 10.1016/j.jcmgh.2018.10.006. Epub 2018 Oct 17.
Cell Mol Gastroenterol Hepatol. 2019.
PMID: 30704983
Free PMC article.
Clinical Trial.
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Hypoxia Positively Regulates the Expression of pH-Sensing G-Protein-Coupled Receptor OGR1 (GPR68).
de Vallière C, Cosin-Roger J, Simmen S, Atrott K, Melhem H, Zeitz J, Madanchi M, Tcymbarevich I, Fried M, Kullak-Ublick GA, Vavricka SR, Misselwitz B, Seuwen K, Wagner CA, Eloranta JJ, Rogler G, Ruiz PA.
de Vallière C, et al. Among authors: simmen s.
Cell Mol Gastroenterol Hepatol. 2016 Jun 25;2(6):796-810. doi: 10.1016/j.jcmgh.2016.06.003. eCollection 2016 Nov.
Cell Mol Gastroenterol Hepatol. 2016.
PMID: 28174749
Free PMC article.
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Hypoxia Reduces the Transcription of Fibrotic Markers in the Intestinal Mucosa.
Simmen S, Maane M, Rogler S, Baebler K, Lang S, Cosin-Roger J, Atrott K, Frey-Wagner I, Spielmann P, Wenger RH, Weder B, Zeitz J, Vavricka SR, Rogler G, de Vallière C, Hausmann M, Ruiz PA.
Simmen S, et al.
Inflamm Intest Dis. 2021 May;6(2):87-100. doi: 10.1159/000513061. Epub 2021 Mar 29.
Inflamm Intest Dis. 2021.
PMID: 34124180
Free PMC article.
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High Prevalence of Extended-Spectrum β-Lactamase Producing Enterobacteriaceae Among Clinical Isolates From Cats and Dogs Admitted to a Veterinary Hospital in Switzerland.
Zogg AL, Simmen S, Zurfluh K, Stephan R, Schmitt SN, Nüesch-Inderbinen M.
Zogg AL, et al. Among authors: simmen s.
Front Vet Sci. 2018 Mar 27;5:62. doi: 10.3389/fvets.2018.00062. eCollection 2018.
Front Vet Sci. 2018.
PMID: 29662886
Free PMC article.
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