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The stability of R-spine defines RAF inhibitor resistance: A comprehensive analysis of oncogenic BRAF mutants with in-frame insertion of αC-β4 loop.
Sci Adv. 2021 Jun 9;7(24):eabg0390. doi: 10.1126/sciadv.abg0390. Print 2021 Jun.
Sci Adv. 2021.
PMID: 34108213
Free PMC article.
Drug resistance in targeted cancer therapies with RAF inhibitors.
Degirmenci U, Yap J, Sim YRM, Qin S, Hu J.
Degirmenci U, et al. Among authors: sim yrm.
Cancer Drug Resist. 2021 Jun 17;4(3):665-683. doi: 10.20517/cdr.2021.36. eCollection 2021.
Cancer Drug Resist. 2021.
PMID: 35582307
Free PMC article.
Review.
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BRAF(V600E) mutation together with loss of Trp53 or pTEN drives the origination of hairy cell leukemia from B-lymphocytes.
Yap J, Yuan J, Ng WH, Chen GB, Sim YRM, Goh KC, Teo J, Lim TYH, Goay SM, Teo JHJ, Lao Z, Lam P, Sabapathy K, Hu J.
Yap J, et al. Among authors: sim yrm.
Mol Cancer. 2023 Aug 5;22(1):125. doi: 10.1186/s12943-023-01817-8.
Mol Cancer. 2023.
PMID: 37543582
Free PMC article.
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