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CD8+ T cells promote HIV latency by remodeling CD4+ T cell metabolism to enhance their survival, quiescence, and stemness.
Mutascio S, Mota T, Franchitti L, Sharma AA, Willemse A, Bergstresser SN, Wang H, Statzu M, Tharp GK, Weiler J, Sékaly RP, Bosinger SE, Paiardini M, Silvestri G, Jones RB, Kulpa DA. Mutascio S, et al. Among authors: silvestri g. Immunity. 2023 May 9;56(5):1132-1147.e6. doi: 10.1016/j.immuni.2023.03.010. Epub 2023 Apr 7. Immunity. 2023. PMID: 37030290 Free PMC article.
Cell-cycle dysregulation in the immunopathogenesis of AIDS.
Paiardini M, Cervasi B, Dunham R, Sumpter B, Radziewicz H, Silvestri G. Paiardini M, et al. Among authors: silvestri g. Immunol Res. 2004;29(1-3):253-68. doi: 10.1385/IR:29:1-3:253. Immunol Res. 2004. PMID: 15181287 Review.
Perturbations of cell cycle control in T cells contribute to the different outcomes of simian immunodeficiency virus infection in rhesus macaques and sooty mangabeys.
Paiardini M, Cervasi B, Sumpter B, McClure HM, Sodora DL, Magnani M, Staprans SI, Piedimonte G, Silvestri G. Paiardini M, et al. Among authors: silvestri g. J Virol. 2006 Jan;80(2):634-42. doi: 10.1128/JVI.80.2.634-642.2006. J Virol. 2006. PMID: 16378966 Free PMC article.
In previous studies, we have shown that the lack of SIV disease progression in SMs is related to lower levels of immune activation and bystander T-cell apoptosis compared to those of pathogenic HIV/SIV infection (G. Silvestri, D. Sodora, R. Koup, M. Paiardini, S. O' …
In previous studies, we have shown that the lack of SIV disease progression in SMs is related to lower levels of immune activation and bysta …
The AIDS resistance of naturally SIV-infected sooty mangabeys is independent of cellular immunity to the virus.
Dunham R, Pagliardini P, Gordon S, Sumpter B, Engram J, Moanna A, Paiardini M, Mandl JN, Lawson B, Garg S, McClure HM, Xu YX, Ibegbu C, Easley K, Katz N, Pandrea I, Apetrei C, Sodora DL, Staprans SI, Feinberg MB, Silvestri G. Dunham R, et al. Among authors: silvestri g. Blood. 2006 Jul 1;108(1):209-17. doi: 10.1182/blood-2005-12-4897. Epub 2006 Mar 7. Blood. 2006. PMID: 16522814 Free PMC article.
Correlates of preserved CD4(+) T cell homeostasis during natural, nonpathogenic simian immunodeficiency virus infection of sooty mangabeys: implications for AIDS pathogenesis.
Sumpter B, Dunham R, Gordon S, Engram J, Hennessy M, Kinter A, Paiardini M, Cervasi B, Klatt N, McClure H, Milush JM, Staprans S, Sodora DL, Silvestri G. Sumpter B, et al. Among authors: silvestri g. J Immunol. 2007 Feb 1;178(3):1680-91. doi: 10.4049/jimmunol.178.3.1680. J Immunol. 2007. PMID: 17237418
1,047 results