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AMPK activation by metformin protects against pulmonary hypertension in rats and relaxes isolated human pulmonary artery.
Abdelazeem H, Tu L, Thuillet R, Ottaviani M, Boulfrad A, Beck T, Senbel A, Mani S, Castier Y, Guyard A, Tran-Dinh A, El-Benna J, Longrois D, Silverstein AM, Guignabert C, Norel X. Abdelazeem H, et al. Among authors: silverstein am. Eur J Pharmacol. 2023 May 5;946:175579. doi: 10.1016/j.ejphar.2023.175579. Epub 2023 Mar 11. Eur J Pharmacol. 2023. PMID: 36914083
Bronchodilation induced by PGE2 is impaired in Group III pulmonary hypertension.
Ozen G, Benyahia C, Mani S, Boukais K, Silverstein AM, Bayles R, Nelsen AC, Castier Y, Danel C, Mal H, Clapp LH, Longrois D, Norel X. Ozen G, et al. Among authors: silverstein am. Br J Pharmacol. 2020 Jan;177(1):161-174. doi: 10.1111/bph.14854. Epub 2019 Oct 31. Br J Pharmacol. 2020. PMID: 31476020 Free PMC article.
Interaction between PGI2 and ET-1 pathways in vascular smooth muscle from Group-III pulmonary hypertension patients.
Ozen G, Benyahia C, Amgoud Y, Patel J, Abdelazeem H, Bouhadoun A, Yung S, Li F, Mahieddine Y, Silverstein AM, Castier Y, Cazes A, Longrois D, Clapp LH, Norel X. Ozen G, et al. Among authors: silverstein am. Prostaglandins Other Lipid Mediat. 2020 Feb;146:106388. doi: 10.1016/j.prostaglandins.2019.106388. Epub 2019 Oct 28. Prostaglandins Other Lipid Mediat. 2020. PMID: 31672620
Downregulation of PGI2 pathway in Pulmonary Hypertension Group-III patients.
Ozen G, Amgoud Y, Abdelazeem H, Mani S, Benyahia C, Bouhadoun A, Tran-Dinh A, Castier Y, Guyard A, Longrois D, Silverstein AM, Norel X. Ozen G, et al. Among authors: silverstein am. Prostaglandins Leukot Essent Fatty Acids. 2020 Sep;160:102158. doi: 10.1016/j.plefa.2020.102158. Epub 2020 Jul 5. Prostaglandins Leukot Essent Fatty Acids. 2020. PMID: 32673988
In search of pulmonary hypertension treatments: Effect of 17β-estradiol on PGI2 pathway in human pulmonary artery.
Amgoud Y, Senbel A, Bouhadoun A, Abdelazeem H, Ozen G, Savané I, Manikpurage HD, Mani S, Tran-Dinh A, Castier Y, Guyard A, Longrois D, Silverstein AM, Norel X. Amgoud Y, et al. Among authors: silverstein am. Prostaglandins Leukot Essent Fatty Acids. 2021 Sep;172:102321. doi: 10.1016/j.plefa.2021.102321. Epub 2021 Aug 9. Prostaglandins Leukot Essent Fatty Acids. 2021. PMID: 34403986
Ex vivo relaxations of pulmonary arteries induced by prostacyclin mimetics are highly dependent of the precontractile agents.
Benyahia C, Ozen G, Orie N, Ledwozyw A, Louedec L, Li F, Senbel AM, Silverstein A, Danel C, Longrois D, Clapp LH, Norel X, Topal G. Benyahia C, et al. Among authors: silverstein a. Prostaglandins Other Lipid Mediat. 2015 Sep;121(Pt A):46-52. doi: 10.1016/j.prostaglandins.2015.09.002. Epub 2015 Sep 8. Prostaglandins Other Lipid Mediat. 2015. PMID: 26362969
177 results