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Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication.
Bozdagi O, Sakurai T, Papapetrou D, Wang X, Dickstein DL, Takahashi N, Kajiwara Y, Yang M, Katz AM, Scattoni ML, Harris MJ, Saxena R, Silverman JL, Crawley JN, Zhou Q, Hof PR, Buxbaum JD. Bozdagi O, et al. Among authors: silverman jl. Mol Autism. 2010 Dec 17;1(1):15. doi: 10.1186/2040-2392-1-15. Mol Autism. 2010. PMID: 21167025 Free PMC article.
Automated three-chambered social approach task for mice.
Yang M, Silverman JL, Crawley JN. Yang M, et al. Among authors: silverman jl. Curr Protoc Neurosci. 2011 Jul;Chapter 8:Unit 8.26. doi: 10.1002/0471142301.ns0826s56. Curr Protoc Neurosci. 2011. PMID: 21732314 Free PMC article.
Low sociability in BTBR T+tf/J mice is independent of partner strain.
Yang M, Abrams DN, Zhang JY, Weber MD, Katz AM, Clarke AM, Silverman JL, Crawley JN. Yang M, et al. Among authors: silverman jl. Physiol Behav. 2012 Dec 5;107(5):649-62. doi: 10.1016/j.physbeh.2011.12.025. Epub 2012 Jan 8. Physiol Behav. 2012. PMID: 22245067 Free PMC article.
Reduced excitatory neurotransmission and mild autism-relevant phenotypes in adolescent Shank3 null mutant mice.
Yang M, Bozdagi O, Scattoni ML, Wöhr M, Roullet FI, Katz AM, Abrams DN, Kalikhman D, Simon H, Woldeyohannes L, Zhang JY, Harris MJ, Saxena R, Silverman JL, Buxbaum JD, Crawley JN. Yang M, et al. Among authors: silverman jl. J Neurosci. 2012 May 9;32(19):6525-41. doi: 10.1523/JNEUROSCI.6107-11.2012. J Neurosci. 2012. PMID: 22573675 Free PMC article.
Long-term exposure to intranasal oxytocin in a mouse autism model.
Bales KL, Solomon M, Jacob S, Crawley JN, Silverman JL, Larke RH, Sahagun E, Puhger KR, Pride MC, Mendoza SP. Bales KL, et al. Among authors: silverman jl. Transl Psychiatry. 2014 Nov 11;4(11):e480. doi: 10.1038/tp.2014.117. Transl Psychiatry. 2014. PMID: 25386957 Free PMC article.
102 results