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Conformational selection, dynamic restriction and the hydrophobic effect coupled to stabilization of the BIR3 domain of the human X-linked inhibitor of apoptosis protein by the tetrapeptide AVPI.
de Souza TL, Sanches D, Gonçalves RB, da RochaPita SS, Pascutti PG, Bianconi ML, de Almeida FC, Silva JL, de Oliveira AC. de Souza TL, et al. Among authors: silva jl. Biophys Chem. 2010 Nov;152(1-3):99-108. doi: 10.1016/j.bpc.2010.08.005. Epub 2010 Aug 17. Biophys Chem. 2010. PMID: 20843595
Mutant p53 aggregates into prion-like amyloid oligomers and fibrils: implications for cancer.
Ano Bom AP, Rangel LP, Costa DC, de Oliveira GA, Sanches D, Braga CA, Gava LM, Ramos CH, Cepeda AO, Stumbo AC, De Moura Gallo CV, Cordeiro Y, Silva JL. Ano Bom AP, et al. Among authors: silva jl. J Biol Chem. 2012 Aug 10;287(33):28152-62. doi: 10.1074/jbc.M112.340638. Epub 2012 Jun 19. J Biol Chem. 2012. PMID: 22715097 Free PMC article.
Prion-like aggregation of mutant p53 in cancer.
Silva JL, De Moura Gallo CV, Costa DC, Rangel LP. Silva JL, et al. Trends Biochem Sci. 2014 Jun;39(6):260-7. doi: 10.1016/j.tibs.2014.04.001. Epub 2014 Apr 26. Trends Biochem Sci. 2014. PMID: 24775734 Review.
Resveratrol prevents p53 aggregation in vitro and in breast cancer cells.
Ferraz da Costa DC, Campos NPC, Santos RA, Guedes-da-Silva FH, Martins-Dinis MMDC, Zanphorlin L, Ramos C, Rangel LP, Silva JL. Ferraz da Costa DC, et al. Among authors: silva jl. Oncotarget. 2018 Jun 26;9(49):29112-29122. doi: 10.18632/oncotarget.25631. eCollection 2018 Jun 26. Oncotarget. 2018. PMID: 30018739 Free PMC article.
858 results