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1,015 results

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De novo design of potent and selective mimics of IL-2 and IL-15.
Silva DA, Yu S, Ulge UY, Spangler JB, Jude KM, Labão-Almeida C, Ali LR, Quijano-Rubio A, Ruterbusch M, Leung I, Biary T, Crowley SJ, Marcos E, Walkey CD, Weitzner BD, Pardo-Avila F, Castellanos J, Carter L, Stewart L, Riddell SR, Pepper M, Bernardes GJL, Dougan M, Garcia KC, Baker D. Silva DA, et al. Nature. 2019 Jan;565(7738):186-191. doi: 10.1038/s41586-018-0830-7. Epub 2019 Jan 9. Nature. 2019. PMID: 30626941 Free PMC article.
Millisecond dynamics of RNA polymerase II translocation at atomic resolution.
Silva DA, Weiss DR, Pardo Avila F, Da LT, Levitt M, Wang D, Huang X. Silva DA, et al. Among authors: da lt. Proc Natl Acad Sci U S A. 2014 May 27;111(21):7665-70. doi: 10.1073/pnas.1315751111. Epub 2014 Apr 21. Proc Natl Acad Sci U S A. 2014. PMID: 24753580 Free PMC article.
Principles for designing proteins with cavities formed by curved β sheets.
Marcos E, Basanta B, Chidyausiku TM, Tang Y, Oberdorfer G, Liu G, Swapna GV, Guan R, Silva DA, Dou J, Pereira JH, Xiao R, Sankaran B, Zwart PH, Montelione GT, Baker D. Marcos E, et al. Among authors: silva da. Science. 2017 Jan 13;355(6321):201-206. doi: 10.1126/science.aah7389. Science. 2017. PMID: 28082595 Free PMC article.
Massively parallel de novo protein design for targeted therapeutics.
Chevalier A, Silva DA, Rocklin GJ, Hicks DR, Vergara R, Murapa P, Bernard SM, Zhang L, Lam KH, Yao G, Bahl CD, Miyashita SI, Goreshnik I, Fuller JT, Koday MT, Jenkins CM, Colvin T, Carter L, Bohn A, Bryan CM, Fernández-Velasco DA, Stewart L, Dong M, Huang X, Jin R, Wilson IA, Fuller DH, Baker D. Chevalier A, et al. Among authors: silva da. Nature. 2017 Oct 5;550(7674):74-79. doi: 10.1038/nature23912. Epub 2017 Sep 27. Nature. 2017. PMID: 28953867 Free PMC article.
Comprehensive computational design of ordered peptide macrocycles.
Hosseinzadeh P, Bhardwaj G, Mulligan VK, Shortridge MD, Craven TW, Pardo-Avila F, Rettie SA, Kim DE, Silva DA, Ibrahim YM, Webb IK, Cort JR, Adkins JN, Varani G, Baker D. Hosseinzadeh P, et al. Among authors: silva da. Science. 2017 Dec 15;358(6369):1461-1466. doi: 10.1126/science.aap7577. Science. 2017. PMID: 29242347 Free PMC article.
De novo protein design by citizen scientists.
Koepnick B, Flatten J, Husain T, Ford A, Silva DA, Bick MJ, Bauer A, Liu G, Ishida Y, Boykov A, Estep RD, Kleinfelter S, Nørgård-Solano T, Wei L, Players F, Montelione GT, DiMaio F, Popović Z, Khatib F, Cooper S, Baker D. Koepnick B, et al. Among authors: silva da. Nature. 2019 Jun;570(7761):390-394. doi: 10.1038/s41586-019-1274-4. Epub 2019 Jun 5. Nature. 2019. PMID: 31168091 Free PMC article.
1,015 results