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T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles.
Nat Commun. 2022 Jun 16;13(1):3460. doi: 10.1038/s41467-022-31160-3.
Nat Commun. 2022.
PMID: 35710644
Free PMC article.
Molecular mechanisms of T cell sensitivity to antigen.
Siller-Farfán JA, Dushek O.
Siller-Farfán JA, et al.
Immunol Rev. 2018 Sep;285(1):194-205. doi: 10.1111/imr.12690.
Immunol Rev. 2018.
PMID: 30129204
Review.
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Developing a graduate training program in Synthetic Biology: SynBioCDT.
Cazimoglu I, Darlington APS, Grigonyte A, Hoskin CEG, Liu J, Oppenheimer R, Siller-Farfán JA, Grierson C, Papachristodoulou A.
Cazimoglu I, et al. Among authors: siller farfan ja.
Synth Biol (Oxf). 2019 Jan 30;4(1):ysz006. doi: 10.1093/synbio/ysz006. eCollection 2019.
Synth Biol (Oxf). 2019.
PMID: 32995533
Free PMC article.
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Using CombiCells, a platform for titration and combinatorial display of cell surface ligands, to study T-cell antigen sensitivity modulation by accessory receptors.
Patel A, Andre V, Eguiguren SB, Barton MI, Burton J, Denham EM, Pettmann J, Mørch AM, Kutuzov MA, Siller-Farfán JA, Dustin ML, van der Merwe PA, Dushek O.
Patel A, et al. Among authors: siller farfan ja.
EMBO J. 2024 Jan;43(1):132-150. doi: 10.1038/s44318-023-00012-1. Epub 2023 Dec 18.
EMBO J. 2024.
PMID: 38177315
Free PMC article.
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Inefficient exploitation of accessory receptors reduces the sensitivity of chimeric antigen receptors.
Burton J, Siller-Farfán JA, Pettmann J, Salzer B, Kutuzov M, van der Merwe PA, Dushek O.
Burton J, et al. Among authors: siller farfan ja.
Proc Natl Acad Sci U S A. 2023 Jan 10;120(2):e2216352120. doi: 10.1073/pnas.2216352120. Epub 2023 Jan 4.
Proc Natl Acad Sci U S A. 2023.
PMID: 36598945
Free PMC article.
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Current and future perspectives of chimeric antigen receptors against glioblastoma.
Zhang J, Siller-Farfán JA.
Zhang J, et al. Among authors: siller farfan ja.
Immunother Adv. 2022 Jun 1;2(1):ltac014. doi: 10.1093/immadv/ltac014. eCollection 2022.
Immunother Adv. 2022.
PMID: 36284838
Free PMC article.
Review.
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