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[Aggressive lymphoma (DLBCL, MCL) - what's new?].
Silkenstedt E, Dreyling M. Silkenstedt E, et al. Dtsch Med Wochenschr. 2022 Nov;147(22):1449-1456. doi: 10.1055/a-1811-9691. Epub 2022 Nov 1. Dtsch Med Wochenschr. 2022. PMID: 36318907 German.
The addition of rituximab to chemotherapy improves overall survival in mantle cell lymphoma-a pooled trials analysis.
Fischer L, Jiang L, Bittenbring JT, Huebel K, Schmidt C, Duell J, Metzner B, Krauter J, Glass B, Huettmann A, Schaefer-Eckart K, Silkenstedt E, Klapper W, Hiddemann W, Unterhalt M, Dreyling M, Hoster E; German Lymphoma Alliance (GLA) and the German Low-Grade Lymphoma Study Group (GLSG). Fischer L, et al. Among authors: silkenstedt e. Ann Hematol. 2023 Oct;102(10):2791-2801. doi: 10.1007/s00277-023-05385-1. Epub 2023 Aug 8. Ann Hematol. 2023. PMID: 37552322 Free PMC article.
Notch1 signaling in NOTCH1-mutated mantle cell lymphoma depends on Delta-Like ligand 4 and is a potential target for specific antibody therapy.
Silkenstedt E, Arenas F, Colom-Sanmartí B, Xargay-Torrent S, Higashi M, Giró A, Rodriguez V, Fuentes P, Aulitzky WE, van der Kuip H, Beà S, Toribio ML, Campo E, López-Guerra M, Colomer D. Silkenstedt E, et al. J Exp Clin Cancer Res. 2019 Nov 1;38(1):446. doi: 10.1186/s13046-019-1458-7. J Exp Clin Cancer Res. 2019. PMID: 31676012 Free PMC article.
PARP14 is a novel target in STAT6 mutant follicular lymphoma.
Mentz M, Keay W, Strobl CD, Antoniolli M, Adolph L, Heide M, Lechner A, Haebe S, Osterode E, Kridel R, Ziegenhain C, Wange LE, Hildebrand JA, Shree T, Silkenstedt E, Staiger AM, Ott G, Horn H, Szczepanowski M, Richter J, Levy R, Rosenwald A, Enard W, Zimber-Strobl U, von Bergwelt-Baildon M, Hiddemann W, Klapper W, Schmidt-Supprian M, Rudelius M, Bararia D, Passerini V, Weigert O. Mentz M, et al. Among authors: silkenstedt e. Leukemia. 2022 Sep;36(9):2281-2292. doi: 10.1038/s41375-022-01641-x. Epub 2022 Jul 18. Leukemia. 2022. PMID: 35851155 Free PMC article.
Specific NOTCH1 antibody targets DLL4-induced proliferation, migration, and angiogenesis in NOTCH1-mutated CLL cells.
López-Guerra M, Xargay-Torrent S, Fuentes P, Roldán J, González-Farré B, Rosich L, Silkenstedt E, García-León MJ, Lee-Vergés E, Giménez N, Giró A, Aymerich M, Villamor N, Delgado J, López-Guillermo A, Puente XS, Campo E, Toribio ML, Colomer D. López-Guerra M, et al. Among authors: silkenstedt e. Oncogene. 2020 Feb;39(6):1185-1197. doi: 10.1038/s41388-019-1053-6. Epub 2019 Oct 15. Oncogene. 2020. PMID: 31616059 Free PMC article.
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