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Oxidation of Hemoglobin Drives a Proatherogenic Polarization of Macrophages in Human Atherosclerosis.
Potor L, Hendrik Z, Patsalos A, Katona É, Méhes G, Póliska S, Csősz É, Kalló G, Komáromi I, Combi Z, Posta N, Sikura KÉ, Pethő D, Oros M, Vereb G, Tóth C, Gergely P, Nagy L, Balla G, Balla J. Potor L, et al. Among authors: sikura ke. Antioxid Redox Signal. 2021 Oct 20;35(12):917-950. doi: 10.1089/ars.2020.8234. Epub 2021 Sep 22. Antioxid Redox Signal. 2021. PMID: 34269613 Free PMC article.
Hemoglobin oxidation generates globin-derived peptides in atherosclerotic lesions and intraventricular hemorrhage of the brain, provoking endothelial dysfunction.
Posta N, Csősz É, Oros M, Pethő D, Potor L, Kalló G, Hendrik Z, Sikura KÉ, Méhes G, Tóth C, Posta J, Balla G, Balla J. Posta N, et al. Among authors: sikura ke. Lab Invest. 2020 Jul;100(7):986-1002. doi: 10.1038/s41374-020-0403-x. Epub 2020 Feb 13. Lab Invest. 2020. PMID: 32054994 Free PMC article.
Potential Role of H-Ferritin in Mitigating Valvular Mineralization.
Sikura KÉ, Potor L, Szerafin T, Zarjou A, Agarwal A, Arosio P, Poli M, Hendrik Z, Méhes G, Oros M, Posta N, Beke L, Fürtös I, Balla G, Balla J. Sikura KÉ, et al. Arterioscler Thromb Vasc Biol. 2019 Mar;39(3):413-431. doi: 10.1161/ATVBAHA.118.312191. Arterioscler Thromb Vasc Biol. 2019. PMID: 30700131 Free PMC article.
Hydrogen sulfide as an anti-calcification stratagem in human aortic valve: Altered biogenesis and mitochondrial metabolism of H2S lead to H2S deficiency in calcific aortic valve disease.
Combi Z, Potor L, Nagy P, Sikura KÉ, Ditrói T, Jurányi EP, Galambos K, Szerafin T, Gergely P, Whiteman M, Torregrossa R, Ding Y, Beke L, Hendrik Z, Méhes G, Balla G, Balla J. Combi Z, et al. Among authors: sikura ke. Redox Biol. 2023 Apr;60:102629. doi: 10.1016/j.redox.2023.102629. Epub 2023 Feb 8. Redox Biol. 2023. PMID: 36780769 Free PMC article.