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Glutathione peroxidase 2 is a metabolic driver of the tumor immune microenvironment and immune checkpoint inhibitor response.
Ahmed KM, Veeramachaneni R, Deng D, Putluri N, Putluri V, Cardenas MF, Wheeler DA, Decker WK, Frederick AI, Kazi S, Sikora AG, Sandulache VC, Frederick MJ. Ahmed KM, et al. Among authors: sikora ag. J Immunother Cancer. 2022 Aug;10(8):e004752. doi: 10.1136/jitc-2022-004752. J Immunother Cancer. 2022. PMID: 36002187 Free PMC article.
Tumor microenvironment modulation enhances immunologic benefit of chemoradiotherapy.
Hanoteau A, Newton JM, Krupar R, Huang C, Liu HC, Gaspero A, Gartrell RD, Saenger YM, Hart TD, Santegoets SJ, Laoui D, Spanos C, Parikh F, Jayaraman P, Zhang B, Van der Burg SH, Van Ginderachter JA, Melief CJM, Sikora AG. Hanoteau A, et al. Among authors: sikora ag. J Immunother Cancer. 2019 Jan 15;7(1):10. doi: 10.1186/s40425-018-0485-9. J Immunother Cancer. 2019. PMID: 30646957 Free PMC article.
Multi-omics Integration Analysis Robustly Predicts High-Grade Patient Survival and Identifies CPT1B Effect on Fatty Acid Metabolism in Bladder Cancer.
Vantaku V, Dong J, Ambati CR, Perera D, Donepudi SR, Amara CS, Putluri V, Ravi SS, Robertson MJ, Piyarathna DWB, Villanueva M, von Rundstedt FC, Karanam B, Ballester LY, Terris MK, Bollag RJ, Lerner SP, Apolo AB, Villanueva H, Lee M, Sikora AG, Lotan Y, Sreekumar A, Coarfa C, Putluri N. Vantaku V, et al. Among authors: sikora ag. Clin Cancer Res. 2019 Jun 15;25(12):3689-3701. doi: 10.1158/1078-0432.CCR-18-1515. Epub 2019 Mar 7. Clin Cancer Res. 2019. PMID: 30846479 Free PMC article.
ERR1 and PGC1α associated mitochondrial alterations correlate with pan-cancer disparity in African Americans.
Piyarathna DWB, Balasubramanian A, Arnold JM, Lloyd SM, Karanam B, Castro P, Ittmann MM, Putluri N, Navone N, Jones JA, Yu W, Sandulache VC, Sikora AG, Michailidis G, Sreekumar A. Piyarathna DWB, et al. Among authors: sikora ag. J Clin Invest. 2019 Mar 28;129(6):2351-2356. doi: 10.1172/JCI127579. J Clin Invest. 2019. PMID: 30920960 Free PMC article.
UDP-glucose 6-dehydrogenase regulates hyaluronic acid production and promotes breast cancer progression.
Arnold JM, Gu F, Ambati CR, Rasaily U, Ramirez-Pena E, Joseph R, Manikkam M, San Martin R, Charles C, Pan Y, Chatterjee SS, Den Hollander P, Zhang W, Nagi C, Sikora AG, Rowley D, Putluri N, Zhang XH, Karanam B, Mani SA, Sreekumar A. Arnold JM, et al. Among authors: sikora ag. Oncogene. 2020 Apr;39(15):3089-3101. doi: 10.1038/s41388-019-0885-4. Epub 2019 Jul 15. Oncogene. 2020. PMID: 31308490 Free PMC article.
Epigenetic loss of AOX1 expression via EZH2 leads to metabolic deregulations and promotes bladder cancer progression.
Vantaku V, Putluri V, Bader DA, Maity S, Ma J, Arnold JM, Rajapakshe K, Donepudi SR, von Rundstedt FC, Devarakonda V, Dubrulle J, Karanam B, McGuire SE, Stossi F, Jain AK, Coarfa C, Cao Q, Sikora AG, Villanueva H, Kavuri SM, Lotan Y, Sreekumar A, Putluri N. Vantaku V, et al. Among authors: sikora ag. Oncogene. 2020 Oct;39(40):6265-6285. doi: 10.1038/s41388-019-0902-7. Epub 2019 Aug 5. Oncogene. 2020. PMID: 31383940 Free PMC article.
171 results