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AAV2-VEGF-B gene therapy failed to induce angiogenesis in ischemic porcine myocardium due to inflammatory responses.
Gene Ther. 2022 Nov;29(10-11):643-652. doi: 10.1038/s41434-022-00322-9. Epub 2022 Feb 7.
Gene Ther. 2022.
PMID: 35132204
Free PMC article.
Large Animal Model for Evaluating the Efficacy of the Gene Therapy in Ischemic Heart.
Korpela H, Siimes S, Ylä-Herttuala S.
Korpela H, et al. Among authors: siimes s.
J Vis Exp. 2021 Sep 2;(175). doi: 10.3791/62833.
J Vis Exp. 2021.
PMID: 34542527
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Endocardial Gene Delivery Using NOGA Catheter System.
Siimes S, Järveläinen N, Korpela H, Ylä-Herttuala S.
Siimes S, et al.
Methods Mol Biol. 2022;2573:179-187. doi: 10.1007/978-1-0716-2707-5_14.
Methods Mol Biol. 2022.
PMID: 36040595
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Gene therapy for ischaemic heart disease and heart failure.
Korpela H, Järveläinen N, Siimes S, Lampela J, Airaksinen J, Valli K, Turunen M, Pajula J, Nurro J, Ylä-Herttuala S.
Korpela H, et al. Among authors: siimes s.
J Intern Med. 2021 Sep;290(3):567-582. doi: 10.1111/joim.13308. Epub 2021 May 25.
J Intern Med. 2021.
PMID: 34033164
Free article.
Review.
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Long-term continuous monitoring of arrhythmias in pigs with insertable cardiac monitors.
Airaksinen J, Siimes S, Hartikainen J, Ylä-Herttuala S.
Airaksinen J, et al. Among authors: siimes s.
Pflugers Arch. 2024 May 4. doi: 10.1007/s00424-024-02962-9. Online ahead of print.
Pflugers Arch. 2024.
PMID: 38703193
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Caridac vein retroinjections provide an efficient approach for global left ventricular gene transfer with adenovirus and adeno-associated virus.
Lampela J, Pajula J, Järveläinen N, Siimes S, Laham-Karam N, Kivelä A, Mushimiyimana I, Nurro J, Hartikainen J, Ylä-Herttuala S.
Lampela J, et al. Among authors: siimes s.
Sci Rep. 2024 Jan 17;14(1):1467. doi: 10.1038/s41598-024-51712-5.
Sci Rep. 2024.
PMID: 38233585
Free PMC article.
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BMP2 gene transfer induces pericardial effusion and inflammatory response in the ischemic porcine myocardium.
Pulkkinen HH, Kivistö-Rahnasto A, Korpela H, Heikkilä M, Järveläinen N, Siimes S, Kilpeläinen L, Laham-Karam N, Ylä-Herttuala S, Laakkonen JP.
Pulkkinen HH, et al. Among authors: siimes s.
Front Cardiovasc Med. 2023 Nov 3;10:1279613. doi: 10.3389/fcvm.2023.1279613. eCollection 2023.
Front Cardiovasc Med. 2023.
PMID: 38028463
Free PMC article.
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