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Nigericin and grisorixin methyl ester from the Algerian soil-living Streptomyces youssoufiensis SF10 strain: a computational study on their epimeric structures and evaluation of glioblastoma stem cells growth inhibition.
Nat Prod Res. 2019 Jan;33(2):266-273. doi: 10.1080/14786419.2018.1446014. Epub 2018 Mar 7.
Nat Prod Res. 2019.
PMID: 29513090
Hybrid Molecules Containing Naphthoquinone and Quinolinedione Scaffolds as Antineoplastic Agents.
Mancini I, Vigna J, Sighel D, Defant A.
Mancini I, et al. Among authors: sighel d.
Molecules. 2022 Aug 3;27(15):4948. doi: 10.3390/molecules27154948.
Molecules. 2022.
PMID: 35956896
Free PMC article.
Review.
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Synthesis of 2,6-Diamino-Substituted Purine Derivatives and Evaluation of Cell Cycle Arrest in Breast and Colorectal Cancer Cells.
Bosco B, Defant A, Messina A, Incitti T, Sighel D, Bozza A, Ciribilli Y, Inga A, Casarosa S, Mancini I.
Bosco B, et al. Among authors: sighel d.
Molecules. 2018 Aug 10;23(8):1996. doi: 10.3390/molecules23081996.
Molecules. 2018.
PMID: 30103421
Free PMC article.
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Inhibition of mitochondrial translation suppresses glioblastoma stem cell growth.
Sighel D, Notarangelo M, Aibara S, Re A, Ricci G, Guida M, Soldano A, Adami V, Ambrosini C, Broso F, Rosatti EF, Longhi S, Buccarelli M, D'Alessandris QG, Giannetti S, Pacioni S, Ricci-Vitiani L, Rorbach J, Pallini R, Roulland S, Amunts A, Mancini I, Modelska A, Quattrone A.
Sighel D, et al.
Cell Rep. 2021 Apr 27;35(4):109024. doi: 10.1016/j.celrep.2021.109024.
Cell Rep. 2021.
PMID: 33910005
Free PMC article.
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Small-Molecule Ebselen Binds to YTHDF Proteins Interfering with the Recognition of N 6-Methyladenosine-Modified RNAs.
Micaelli M, Dalle Vedove A, Cerofolini L, Vigna J, Sighel D, Zaccara S, Bonomo I, Poulentzas G, Rosatti EF, Cazzanelli G, Alunno L, Belli R, Peroni D, Dassi E, Murakami S, Jaffrey SR, Fragai M, Mancini I, Lolli G, Quattrone A, Provenzani A.
Micaelli M, et al. Among authors: sighel d.
ACS Pharmacol Transl Sci. 2022 Sep 14;5(10):872-891. doi: 10.1021/acsptsci.2c00008. eCollection 2022 Oct 14.
ACS Pharmacol Transl Sci. 2022.
PMID: 36268123
Free PMC article.
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Screening Approaches for Targeting Ribonucleoprotein Complexes: A New Dimension for Drug Discovery.
D'Agostino VG, Sighel D, Zucal C, Bonomo I, Micaelli M, Lolli G, Provenzani A, Quattrone A, Adami V.
D'Agostino VG, et al. Among authors: sighel d.
SLAS Discov. 2019 Mar;24(3):314-331. doi: 10.1177/2472555218818065. Epub 2019 Jan 7.
SLAS Discov. 2019.
PMID: 30616427
Free article.
Review.
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Expanding the Chemical Space of Arsenicin A-C Related Polyarsenicals and Evaluation of Some Analogs as Inhibitors of Glioblastoma Stem Cell Growth.
Vigna J, Sighel D, Rosatti EF, Defant A, Pancher M, Sidarovich V, Quattrone A, Mancini I.
Vigna J, et al. Among authors: sighel d.
Mar Drugs. 2023 Mar 17;21(3):186. doi: 10.3390/md21030186.
Mar Drugs. 2023.
PMID: 36976235
Free PMC article.
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Streptogramin A derivatives as mitochondrial translation inhibitors to suppress glioblastoma stem cell growth.
Sighel D, Battistini G, Rosatti EF, Vigna J, Pavan M, Belli R, Peroni D, Alessandrini F, Longhi S, Pancher M, Rorbach J, Moro S, Quattrone A, Mancini I.
Sighel D, et al.
Eur J Med Chem. 2023 Jan 15;246:114979. doi: 10.1016/j.ejmech.2022.114979. Epub 2022 Nov 30.
Eur J Med Chem. 2023.
PMID: 36495628
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