Sigal M - Search Results

1

R-spondin/YAP axis promotes gastric oxyntic gland regeneration and Helicobacter pylori-associated metaplasia in mice.

Fischer AS, Müllerke S, Arnold A, Heuberger J, Berger H, Lin M, Mollenkopf HJ, Wizenty J, Horst D, Tacke F, Sigal M. Fischer AS, et al. Among authors: sigal m. J Clin Invest. 2022 Nov 1;132(21):e151363. doi: 10.1172/JCI151363. J Clin Invest. 2022. PMID: 36099044 Free PMC article.

2

Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis.

Sigal M, Logan CY, Kapalczynska M, Mollenkopf HJ, Berger H, Wiedenmann B, Nusse R, Amieva MR, Meyer TF. Sigal M, et al. Nature. 2017 Aug 24;548(7668):451-455. doi: 10.1038/nature23642. Epub 2017 Aug 16. Nature. 2017. PMID: 28813421

3

Helicobacter pylori Depletes Cholesterol in Gastric Glands to Prevent Interferon Gamma Signaling and Escape the Inflammatory Response.

Morey P, Pfannkuch L, Pang E, Boccellato F, Sigal M, Imai-Matsushima A, Dyer V, Koch M, Mollenkopf HJ, Schlaermann P, Meyer TF. Morey P, et al. Among authors: sigal m. Gastroenterology. 2018 Apr;154(5):1391-1404.e9. doi: 10.1053/j.gastro.2017.12.008. Epub 2017 Dec 19. Gastroenterology. 2018. PMID: 29273450 Free article.

4

R-spondin-3 induces secretory, antimicrobial Lgr5⁺ cells in the stomach.

Sigal M, Reinés MDM, Müllerke S, Fischer C, Kapalczynska M, Berger H, Bakker ERM, Mollenkopf HJ, Rothenberg ME, Wiedenmann B, Sauer S, Meyer TF. Sigal M, et al. Nat Cell Biol. 2019 Jul;21(7):812-823. doi: 10.1038/s41556-019-0339-9. Epub 2019 Jun 24. Nat Cell Biol. 2019. PMID: 31235935

5

The Role of Wnt and R-spondin in the Stomach During Health and Disease.

Fischer AS, Sigal M. Fischer AS, et al. Among authors: sigal m. Biomedicines. 2019 Jun 19;7(2):44. doi: 10.3390/biomedicines7020044. Biomedicines. 2019. PMID: 31248166 Free PMC article. Review.

6

R-spondin 3 promotes stem cell recovery and epithelial regeneration in the colon.

Harnack C, Berger H, Antanaviciute A, Vidal R, Sauer S, Simmons A, Meyer TF, Sigal M. Harnack C, et al. Among authors: sigal m. Nat Commun. 2019 Sep 25;10(1):4368. doi: 10.1038/s41467-019-12349-5. Nat Commun. 2019. PMID: 31554819 Free PMC article.

7

Responses of gastric epithelial stem cells and their niche to Helicobacter pylori infection.

Wizenty J, Tacke F, Sigal M. Wizenty J, et al. Among authors: sigal m. Ann Transl Med. 2020 Apr;8(8):568. doi: 10.21037/atm.2020.02.178. Ann Transl Med. 2020. PMID: 32775369 Free PMC article. Review.

8

Epithelial response to IFN-γ promotes SARS-CoV-2 infection.

Heuberger J, Trimpert J, Vladimirova D, Goosmann C, Lin M, Schmuck R, Mollenkopf HJ, Brinkmann V, Tacke F, Osterrieder N, Sigal M. Heuberger J, et al. Among authors: sigal m. EMBO Mol Med. 2021 Apr 9;13(4):e13191. doi: 10.15252/emmm.202013191. Epub 2021 Mar 3. EMBO Mol Med. 2021. PMID: 33544398 Free PMC article.

9

Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells.

Iftekhar A, Berger H, Bouznad N, Heuberger J, Boccellato F, Dobrindt U, Hermeking H, Sigal M, Meyer TF. Iftekhar A, et al. Among authors: sigal m. Nat Commun. 2021 Feb 12;12(1):1003. doi: 10.1038/s41467-021-21162-y. Nat Commun. 2021. PMID: 33579932 Free PMC article.

10

High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53.

Heuberger J, Grinat J, Kosel F, Liu L, Kunz S, Vidal RO, Keil M, Haybaeck J, Robine S, Louvard D, Regenbrecht C, Sporbert A, Sauer S, von Eyss B, Sigal M, Birchmeier W. Heuberger J, et al. Among authors: sigal m. Proc Natl Acad Sci U S A. 2021 Jun 1;118(22):e2019699118. doi: 10.1073/pnas.2019699118. Proc Natl Acad Sci U S A. 2021. PMID: 34039707 Free PMC article.

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