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Dietary L-Tryptophan consumption determines the number of colonic regulatory T cells and susceptibility to colitis via GPR15.
Van NT, Zhang K, Wigmore RM, Kennedy AI, DaSilva CR, Huang J, Ambelil M, Villagomez JH, O'Connor GJ, Longman RS, Cao M, Snook AE, Platten M, Kasenty G, Sigal LJ, Prendergast GC, Kim SV. Van NT, et al. Among authors: sigal lj. Nat Commun. 2023 Nov 14;14(1):7363. doi: 10.1038/s41467-023-43211-4. Nat Commun. 2023. PMID: 37963876 Free PMC article.
IFN-β Acts on Monocytes to Ameliorate CNS Autoimmunity by Inhibiting Proinflammatory Cross-Talk Between Monocytes and Th Cells.
Rasouli J, Casella G, Ishikawa LLW, Thome R, Boehm A, Ertel A, Melo-Silva CR, Mari ER, Porazzi P, Zhang W, Xiao D, Sigal LJ, Fortina P, Zhang GX, Rostami A, Ciric B. Rasouli J, et al. Among authors: sigal lj. Front Immunol. 2021 Jun 4;12:679498. doi: 10.3389/fimmu.2021.679498. eCollection 2021. Front Immunol. 2021. PMID: 34149716 Free PMC article.
Dysregulated anti-viral innate immune cascade during aging.
Stotesbury C, Sigal LJ. Stotesbury C, et al. Among authors: sigal lj. Aging (Albany NY). 2021 Jan 27;13(2):1566-1567. doi: 10.18632/aging.202588. Epub 2021 Jan 27. Aging (Albany NY). 2021. PMID: 33510045 Free PMC article. No abstract available.
Resistance to lethal ectromelia virus infection requires Type I interferon receptor in natural killer cells and monocytes but not in adaptive immune or parenchymal cells.
Melo-Silva CR, Alves-Peixoto P, Heath N, Tang L, Montoya B, Knudson CJ, Stotesbury C, Ferez M, Wong E, Sigal LJ. Melo-Silva CR, et al. Among authors: sigal lj. PLoS Pathog. 2021 May 20;17(5):e1009593. doi: 10.1371/journal.ppat.1009593. eCollection 2021 May. PLoS Pathog. 2021. PMID: 34015056 Free PMC article.
73 results