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Illuminating Dark Chemical Matter Using the Cell Painting Assay.
Pahl A, Liu J, Patil S, Rezaei Adariani S, Schölermann B, Warmers J, Bonowski J, Koska S, Akbulut Y, Seitz C, Sievers S, Ziegler S, Waldmann H. Pahl A, et al. Among authors: sievers s. J Med Chem. 2024 Apr 30. doi: 10.1021/acs.jmedchem.4c00160. Online ahead of print. J Med Chem. 2024. PMID: 38687818
Discovery of Covalent Inhibitors Targeting the Transcriptional Enhanced Associate Domain Central Pocket.
Karatas H, Akbarzadeh M, Adihou H, Hahne G, Pobbati AV, Yihui Ng E, Guéret SM, Sievers S, Pahl A, Metz M, Zinken S, Dötsch L, Nowak C, Thavam S, Friese A, Kang C, Hong W, Waldmann H. Karatas H, et al. Among authors: sievers s. J Med Chem. 2020 Oct 22;63(20):11972-11989. doi: 10.1021/acs.jmedchem.0c01275. Epub 2020 Oct 1. J Med Chem. 2020. PMID: 32907324 Free PMC article.
Phenotypic Discovery of Triazolo[1,5-c]quinazolines as a First-In-Class Bone Morphogenetic Protein Amplifier Chemotype.
Wesseler F, Lohmann S, Riege D, Halver J, Roth A, Pichlo C, Weber S, Takamiya M, Müller E, Ketzel J, Flegel J, Gihring A, Rastegar S, Bertrand J, Baumann U, Knippschild U, Peifer C, Sievers S, Waldmann H, Schade D. Wesseler F, et al. Among authors: sievers s. J Med Chem. 2022 Nov 24;65(22):15263-15281. doi: 10.1021/acs.jmedchem.2c01199. Epub 2022 Nov 8. J Med Chem. 2022. PMID: 36346705
The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast Differentiation.
Flegel J, Shaaban S, Jia ZJ, Schulte B, Lian Y, Krzyzanowski A, Metz M, Schneidewind T, Wesseler F, Flegel A, Reich A, Brause A, Xue G, Zhang M, Dötsch L, Stender ID, Hoffmann JE, Scheel R, Janning P, Rastinejad F, Schade D, Strohmann C, Antonchick AP, Sievers S, Moura-Alves P, Ziegler S, Waldmann H. Flegel J, et al. Among authors: sievers s. J Med Chem. 2022 Dec 22;65(24):16268-16289. doi: 10.1021/acs.jmedchem.2c00956. Epub 2022 Dec 2. J Med Chem. 2022. PMID: 36459434 Free PMC article.
185 results