Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

42 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes.
Mueller S, Engleitner T, Maresch R, Zukowska M, Lange S, Kaltenbacher T, Konukiewitz B, Öllinger R, Zwiebel M, Strong A, Yen HY, Banerjee R, Louzada S, Fu B, Seidler B, Götzfried J, Schuck K, Hassan Z, Arbeiter A, Schönhuber N, Klein S, Veltkamp C, Friedrich M, Rad L, Barenboim M, Ziegenhain C, Hess J, Dovey OM, Eser S, Parekh S, Constantino-Casas F, de la Rosa J, Sierra MI, Fraga M, Mayerle J, Klöppel G, Cadiñanos J, Liu P, Vassiliou G, Weichert W, Steiger K, Enard W, Schmid RM, Yang F, Unger K, Schneider G, Varela I, Bradley A, Saur D, Rad R. Mueller S, et al. Among authors: sierra mi. Nature. 2018 Feb 1;554(7690):62-68. doi: 10.1038/nature25459. Epub 2018 Jan 24. Nature. 2018. PMID: 29364867 Free PMC article.
Epigenetics of Aging.
Sierra MI, Fernández AF, Fraga MF. Sierra MI, et al. Curr Genomics. 2015 Dec;16(6):435-40. doi: 10.2174/1389202916666150817203459. Curr Genomics. 2015. PMID: 27019618 Free PMC article.
Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases.
Lynch CJ, Bernad R, Martínez-Val A, Shahbazi MN, Nóbrega-Pereira S, Calvo I, Blanco-Aparicio C, Tarantino C, Garreta E, Richart-Ginés L, Alcazar N, Graña-Castro O, Gómez-Lopez G, Aksoy I, Muñoz-Martín M, Martinez S, Ortega S, Prieto S, Simboeck E, Camasses A, Stephan-Otto Attolini C, Fernandez AF, Sierra MI, Fraga MF, Pastor J, Fisher D, Montserrat N, Savatier P, Muñoz J, Zernicka-Goetz M, Serrano M. Lynch CJ, et al. Among authors: sierra mi. Nat Cell Biol. 2020 Oct;22(10):1223-1238. doi: 10.1038/s41556-020-0573-1. Epub 2020 Sep 28. Nat Cell Biol. 2020. PMID: 32989249 Free article.
No genome-wide DNA methylation changes found associated with medium-term reduced graphene oxide exposure in human lung epithelial cells.
Pérez RF, Soto Fernández AY, Bousquets Muñoz P, Sierra MI, Tejedor JR, Morales-Sánchez P, Valdés AF, Santamaría R, Blanco C, Torrecillas R, Fraga MF, Fernández AF. Pérez RF, et al. Among authors: sierra mi. Epigenetics. 2020 Mar;15(3):283-293. doi: 10.1080/15592294.2019.1666650. Epub 2019 Sep 18. Epigenetics. 2020. PMID: 31512544 Free PMC article.
SDHC Promoter Methylation, a Novel Pathogenic Mechanism in Parasympathetic Paragangliomas.
Bernardo-Castiñeira C, Valdés N, Sierra MI, Sáenz-de-Santa-María I, Bayón GF, Perez RF, Fernández AF, Fraga MF, Astudillo A, Menéndez R, Fernández B, Del Olmo M, Suarez C, Chiara MD. Bernardo-Castiñeira C, et al. Among authors: sierra mi. J Clin Endocrinol Metab. 2018 Jan 1;103(1):295-305. doi: 10.1210/jc.2017-01702. J Clin Endocrinol Metab. 2018. PMID: 29126304
Epigenetic dysregulation of TET2 in human glioblastoma.
García MG, Carella A, Urdinguio RG, Bayón GF, Lopez V, Tejedor JR, Sierra MI, García-Toraño E, Santamarina P, Perez RF, Mangas C, Astudillo A, Corte-Torres MD, Sáenz-de-Santa-María I, Chiara MD, Fernández AF, Fraga MF. García MG, et al. Among authors: sierra mi. Oncotarget. 2018 May 25;9(40):25922-25934. doi: 10.18632/oncotarget.25406. eCollection 2018 May 25. Oncotarget. 2018. PMID: 29899831 Free PMC article.
Age-associated hydroxymethylation in human bone-marrow mesenchymal stem cells.
Toraño EG, Bayón GF, Del Real Á, Sierra MI, García MG, Carella A, Belmonte T, Urdinguio RG, Cubillo I, García-Castro J, Delgado-Calle J, Pérez-Campo FM, Riancho JA, Fraga MF, Fernández AF. Toraño EG, et al. Among authors: sierra mi. J Transl Med. 2016 Jul 8;14(1):207. doi: 10.1186/s12967-016-0966-x. J Transl Med. 2016. PMID: 27393146 Free PMC article.
Epigenetic downregulation of TET3 reduces genome-wide 5hmC levels and promotes glioblastoma tumorigenesis.
Carella A, Tejedor JR, García MG, Urdinguio RG, Bayón GF, Sierra M, López V, García-Toraño E, Santamarina-Ojeda P, Pérez RF, Bigot T, Mangas C, Corte-Torres MD, Sáenz-de-Santa-María I, Mollejo M, Meléndez B, Astudillo A, Chiara MD, Fernández AF, Fraga MF. Carella A, et al. Int J Cancer. 2020 Jan 15;146(2):373-387. doi: 10.1002/ijc.32520. Epub 2019 Jul 1. Int J Cancer. 2020. PMID: 31211412 Free article.
42 results