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CDK4/6-MEK Inhibition in MPNSTs Causes Plasma Cell Infiltration, Sensitization to PD-L1 Blockade, and Tumor Regression.
Kohlmeyer JL, Lingo JJ, Kaemmer CA, Scherer A, Warrier A, Voigt E, Raygoza Garay JA, McGivney GR, Brockman QR, Tang A, Calizo A, Pollard K, Zhang X, Hirbe AC, Pratilas CA, Leidinger M, Breheny P, Chimenti MS, Sieren JC, Monga V, Tanas MR, Meyerholz DK, Darbro BW, Dodd RD, Quelle DE. Kohlmeyer JL, et al. Among authors: sieren jc. Clin Cancer Res. 2023 Sep 1;29(17):3484-3497. doi: 10.1158/1078-0432.CCR-23-0749. Clin Cancer Res. 2023. PMID: 37410426 Free PMC article.
RABL6A Is an Essential Driver of MPNSTs that Negatively Regulates the RB1 Pathway and Sensitizes Tumor Cells to CDK4/6 Inhibitors.
Kohlmeyer JL, Kaemmer CA, Pulliam C, Maharjan CK, Samayoa AM, Major HJ, Cornick KE, Knepper-Adrian V, Khanna R, Sieren JC, Leidinger MR, Meyerholz DK, Zamba KD, Weimer JM, Dodd RD, Darbro BW, Tanas MR, Quelle DE. Kohlmeyer JL, et al. Among authors: sieren jc. Clin Cancer Res. 2020 Jun 15;26(12):2997-3011. doi: 10.1158/1078-0432.CCR-19-2706. Epub 2020 Feb 21. Clin Cancer Res. 2020. PMID: 32086342 Free PMC article.
A porcine model of neurofibromatosis type 1 that mimics the human disease.
White KA, Swier VJ, Cain JT, Kohlmeyer JL, Meyerholz DK, Tanas MR, Uthoff J, Hammond E, Li H, Rohret FA, Goeken A, Chan CH, Leidinger MR, Umesalma S, Wallace MR, Dodd RD, Panzer K, Tang AH, Darbro BW, Moutal A, Cai S, Li W, Bellampalli SS, Khanna R, Rogers CS, Sieren JC, Quelle DE, Weimer JM. White KA, et al. Among authors: sieren jc. JCI Insight. 2018 Jun 21;3(12):e120402. doi: 10.1172/jci.insight.120402. eCollection 2018 Jun 21. JCI Insight. 2018. PMID: 29925695 Free PMC article.
Porcine cancer models for translational oncology.
Sieren JC, Quelle D, Meyerholz DK, Rogers CS. Sieren JC, et al. Mol Cell Oncol. 2014 Nov 11;1(4):e969626. doi: 10.4161/23723548.2014.969626. eCollection 2014 Oct-Dec. Mol Cell Oncol. 2014. PMID: 27308376 Free PMC article.
Assessment of nociception and related quality-of-life measures in a porcine model of neurofibromatosis type 1.
Khanna R, Moutal A, White KA, Chefdeville A, Negrao de Assis P, Cai S, Swier VJ, Bellampalli SS, Giunta MD, Darbro BW, Quelle DE, Sieren JC, Wallace MR, Rogers CS, Meyerholz DK, Weimer JM. Khanna R, et al. Among authors: sieren jc. Pain. 2019 Nov;160(11):2473-2486. doi: 10.1097/j.pain.0000000000001648. Pain. 2019. PMID: 31246731 Free PMC article.
Longitudinal phenotype development in a minipig model of neurofibromatosis type 1.
Uthoff J, Larson J, Sato TS, Hammond E, Schroeder KE, Rohret F, Rogers CS, Quelle DE, Darbro BW, Khanna R, Weimer JM, Meyerholz DK, Sieren JC. Uthoff J, et al. Among authors: sieren jc. Sci Rep. 2020 Mar 19;10(1):5046. doi: 10.1038/s41598-020-61251-4. Sci Rep. 2020. PMID: 32193437 Free PMC article.
Approaches to Evaluate Lung Inflammation in Translational Research.
Meyerholz DK, Sieren JC, Beck AP, Flaherty HA. Meyerholz DK, et al. Among authors: sieren jc. Vet Pathol. 2018 Jan;55(1):42-52. doi: 10.1177/0300985817726117. Epub 2017 Aug 16. Vet Pathol. 2018. PMID: 28812529 Free PMC article. Review.
55 results