Sienski G - Search Results

1

PICALM Rescues Endocytic Defects Caused by the Alzheimer's Disease Risk Factor APOE4.

Narayan P, Sienski G, Bonner JM, Lin YT, Seo J, Baru V, Haque A, Milo B, Akay LA, Graziosi A, Freyzon Y, Landgraf D, Hesse WR, Valastyan J, Barrasa MI, Tsai LH, Lindquist S. Narayan P, et al. Among authors: sienski g. Cell Rep. 2020 Oct 6;33(1):108224. doi: 10.1016/j.celrep.2020.108224. Cell Rep. 2020. PMID: 33027662 Free PMC article.

2

APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia.

Sienski G, Narayan P, Bonner JM, Kory N, Boland S, Arczewska AA, Ralvenius WT, Akay L, Lockshin E, He L, Milo B, Graziosi A, Baru V, Lewis CA, Kellis M, Sabatini DM, Tsai LH, Lindquist S. Sienski G, et al. Sci Transl Med. 2021 Mar 3;13(583):eaaz4564. doi: 10.1126/scitranslmed.aaz4564. Sci Transl Med. 2021. PMID: 33658354 Free PMC article.

3

The rhino-deadlock-cutoff complex licenses noncanonical transcription of dual-strand piRNA clusters in Drosophila.

Mohn F, Sienski G, Handler D, Brennecke J. Mohn F, et al. Among authors: sienski g. Cell. 2014 Jun 5;157(6):1364-1379. doi: 10.1016/j.cell.2014.04.031. Cell. 2014. PMID: 24906153 Free article.

4

Transcriptional silencing of transposons by Piwi and maelstrom and its impact on chromatin state and gene expression.

Sienski G, Dönertas D, Brennecke J. Sienski G, et al. Cell. 2012 Nov 21;151(5):964-80. doi: 10.1016/j.cell.2012.10.040. Epub 2012 Nov 15. Cell. 2012. PMID: 23159368 Free PMC article.

5

Drosophila Gtsf1 is an essential component of the Piwi-mediated transcriptional silencing complex.

Dönertas D, Sienski G, Brennecke J. Dönertas D, et al. Among authors: sienski g. Genes Dev. 2013 Aug 1;27(15):1693-705. doi: 10.1101/gad.221150.113. Genes Dev. 2013. PMID: 23913922 Free PMC article.

6

Silencio/CG9754 connects the Piwi-piRNA complex to the cellular heterochromatin machinery.

Sienski G, Batki J, Senti KA, Dönertas D, Tirian L, Meixner K, Brennecke J. Sienski G, et al. Genes Dev. 2015 Nov 1;29(21):2258-71. doi: 10.1101/gad.271908.115. Epub 2015 Oct 22. Genes Dev. 2015. PMID: 26494711 Free PMC article.

7

Panoramix SUMOylation on chromatin connects the piRNA pathway to the cellular heterochromatin machinery.

Andreev VI, Yu C, Wang J, Schnabl J, Tirian L, Gehre M, Handler D, Duchek P, Novatchkova M, Baumgartner L, Meixner K, Sienski G, Patel DJ, Brennecke J. Andreev VI, et al. Among authors: sienski g. Nat Struct Mol Biol. 2022 Feb;29(2):130-142. doi: 10.1038/s41594-022-00721-x. Epub 2022 Feb 16. Nat Struct Mol Biol. 2022. PMID: 35173350

8

Efficient CRISPR/Cas9 plasmids for rapid and versatile genome editing in Drosophila.

Gokcezade J, Sienski G, Duchek P. Gokcezade J, et al. Among authors: sienski g. G3 (Bethesda). 2014 Sep 17;4(11):2279-82. doi: 10.1534/g3.114.014126. G3 (Bethesda). 2014. PMID: 25236734 Free PMC article.

9

Universal toxin-based selection for precise genome engineering in human cells.

Li S, Akrap N, Cerboni S, Porritt MJ, Wimberger S, Lundin A, Möller C, Firth M, Gordon E, Lazovic B, Sieńska A, Pane LS, Coelho MA, Ciotta G, Pellegrini G, Sini M, Xu X, Mitra S, Bohlooly-Y M, Taylor BJM, Sienski G, Maresca M. Li S, et al. Among authors: sienski g. Nat Commun. 2021 Jan 21;12(1):497. doi: 10.1038/s41467-020-20810-z. Nat Commun. 2021. PMID: 33479216 Free PMC article.

10

Harnessing DSB repair to promote efficient homology-dependent and -independent prime editing.

Peterka M, Akrap N, Li S, Wimberger S, Hsieh PP, Degtev D, Bestas B, Barr J, van de Plassche S, Mendoza-Garcia P, Šviković S, Sienski G, Firth M, Maresca M. Peterka M, et al. Among authors: sienski g. Nat Commun. 2022 Mar 24;13(1):1240. doi: 10.1038/s41467-022-28771-1. Nat Commun. 2022. PMID: 35332138 Free PMC article.

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