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Photodynamic Therapy Combined with Bcl-2/Bcl-xL Inhibition Increases the Noxa/Mcl-1 Ratio Independent of Usp9X and Synergistically Enhances Apoptosis in Glioblastoma.
Golla C, Bilal M, Dwucet A, Bader N, Anthonymuthu J, Heiland T, Pruss M, Westhoff MA, Siegelin MD, Capanni F, Wirtz CR, Kast RE, Halatsch ME, Karpel-Massler G. Golla C, et al. Among authors: siegelin md. Cancers (Basel). 2021 Aug 17;13(16):4123. doi: 10.3390/cancers13164123. Cancers (Basel). 2021. PMID: 34439278 Free PMC article.
Olanzapine inhibits proliferation, migration and anchorage-independent growth in human glioblastoma cell lines and enhances temozolomide's antiproliferative effect.
Karpel-Massler G, Kast RE, Westhoff MA, Dwucet A, Welscher N, Nonnenmacher L, Hlavac M, Siegelin MD, Wirtz CR, Debatin KM, Halatsch ME. Karpel-Massler G, et al. Among authors: siegelin md. J Neurooncol. 2015 Mar;122(1):21-33. doi: 10.1007/s11060-014-1688-7. Epub 2014 Dec 19. J Neurooncol. 2015. PMID: 25524815
PARP inhibition restores extrinsic apoptotic sensitivity in glioblastoma.
Karpel-Massler G, Pareja F, Aimé P, Shu C, Chau L, Westhoff MA, Halatsch ME, Crary JF, Canoll P, Siegelin MD. Karpel-Massler G, et al. Among authors: siegelin md. PLoS One. 2014 Dec 22;9(12):e114583. doi: 10.1371/journal.pone.0114583. eCollection 2014. PLoS One. 2014. PMID: 25531448 Free PMC article.
A critical evaluation of PI3K inhibition in Glioblastoma and Neuroblastoma therapy.
Westhoff MA, Karpel-Massler G, Brühl O, Enzenmüller S, La Ferla-Brühl K, Siegelin MD, Nonnenmacher L, Debatin KM. Westhoff MA, et al. Among authors: siegelin md. Mol Cell Ther. 2014 Oct 27;2:32. doi: 10.1186/2052-8426-2-32. eCollection 2014. Mol Cell Ther. 2014. PMID: 26056598 Free PMC article. Review.
A Potential Role for the Inhibition of PI3K Signaling in Glioblastoma Therapy.
Ströbele S, Schneider M, Schneele L, Siegelin MD, Nonnenmacher L, Zhou S, Karpel-Massler G, Westhoff MA, Halatsch ME, Debatin KM. Ströbele S, et al. Among authors: siegelin md. PLoS One. 2015 Jun 29;10(6):e0131670. doi: 10.1371/journal.pone.0131670. eCollection 2015. PLoS One. 2015. PMID: 26121251 Free PMC article.
A paired comparison between glioblastoma "stem cells" and differentiated cells.
Schneider M, Ströbele S, Nonnenmacher L, Siegelin MD, Tepper M, Stroh S, Hasslacher S, Enzenmüller S, Strauss G, Baumann B, Karpel-Massler G, Westhoff MA, Debatin KM, Halatsch ME. Schneider M, et al. Among authors: siegelin md. Int J Cancer. 2016 Apr 1;138(7):1709-18. doi: 10.1002/ijc.29908. Epub 2015 Nov 17. Int J Cancer. 2016. PMID: 26519239 Free article.
A Synthetic Cell-Penetrating Dominant-Negative ATF5 Peptide Exerts Anticancer Activity against a Broad Spectrum of Treatment-Resistant Cancers.
Karpel-Massler G, Horst BA, Shu C, Chau L, Tsujiuchi T, Bruce JN, Canoll P, Greene LA, Angelastro JM, Siegelin MD. Karpel-Massler G, et al. Among authors: siegelin md. Clin Cancer Res. 2016 Sep 15;22(18):4698-711. doi: 10.1158/1078-0432.CCR-15-2827. Epub 2016 Apr 28. Clin Cancer Res. 2016. PMID: 27126996 Free PMC article.
114 results