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Creatine-mediated crosstalk between adipocytes and cancer cells regulates obesity-driven breast cancer.
Maguire OA, Ackerman SE, Szwed SK, Maganti AV, Marchildon F, Huang X, Kramer DJ, Rosas-Villegas A, Gelfer RG, Turner LE, Ceballos V, Hejazi A, Samborska B, Rahbani JF, Dykstra CB, Annis MG, Luo JD, Carroll TS, Jiang CS, Dannenberg AJ, Siegel PM, Tersey SA, Mirmira RG, Kazak L, Cohen P. Maguire OA, et al. Among authors: siegel pm. Cell Metab. 2021 Mar 2;33(3):499-512.e6. doi: 10.1016/j.cmet.2021.01.018. Epub 2021 Feb 16. Cell Metab. 2021. PMID: 33596409 Free PMC article.
Osteoactivin promotes breast cancer metastasis to bone.
Rose AA, Pepin F, Russo C, Abou Khalil JE, Hallett M, Siegel PM. Rose AA, et al. Among authors: siegel pm. Mol Cancer Res. 2007 Oct;5(10):1001-14. doi: 10.1158/1541-7786.MCR-07-0119. Mol Cancer Res. 2007. PMID: 17951401
Claudin-2 is selectively enriched in and promotes the formation of breast cancer liver metastases through engagement of integrin complexes.
Tabariès S, Dong Z, Annis MG, Omeroglu A, Pepin F, Ouellet V, Russo C, Hassanain M, Metrakos P, Diaz Z, Basik M, Bertos N, Park M, Guettier C, Adam R, Hallett M, Siegel PM. Tabariès S, et al. Among authors: siegel pm. Oncogene. 2011 Mar 17;30(11):1318-28. doi: 10.1038/onc.2010.518. Epub 2010 Nov 15. Oncogene. 2011. PMID: 21076473
AMPK is a negative regulator of the Warburg effect and suppresses tumor growth in vivo.
Faubert B, Boily G, Izreig S, Griss T, Samborska B, Dong Z, Dupuy F, Chambers C, Fuerth BJ, Viollet B, Mamer OA, Avizonis D, DeBerardinis RJ, Siegel PM, Jones RG. Faubert B, et al. Among authors: siegel pm. Cell Metab. 2013 Jan 8;17(1):113-24. doi: 10.1016/j.cmet.2012.12.001. Epub 2012 Dec 27. Cell Metab. 2013. PMID: 23274086 Free PMC article.
165 results