Siegal G - Search Results

1

Siegal G, Selenko P. Siegal G, et al. J Magn Reson. 2019 Sep;306:202-212. doi: 10.1016/j.jmr.2019.07.018. Epub 2019 Jul 13. J Magn Reson. 2019. PMID: 31358370 Free article. Review.

2

NMR in structure-based drug design.

Carneiro MG, Ab E, Theisgen S, Siegal G. Carneiro MG, et al. Among authors: siegal g. Essays Biochem. 2017 Nov 8;61(5):485-493. doi: 10.1042/EBC20170037. Print 2017 Nov 8. Essays Biochem. 2017. PMID: 29118095 Review.

3

Development of a dual cell, flow-injection sample holder, and NMR probe for comparative ligand-binding studies.

Marquardsen T, Hofmann M, Hollander JG, Loch CM, Kiihne SR, Engelke F, Siegal G. Marquardsen T, et al. Among authors: siegal g. J Magn Reson. 2006 Sep;182(1):55-65. doi: 10.1016/j.jmr.2006.05.018. Epub 2006 Jun 30. J Magn Reson. 2006. PMID: 16814582

4

Automatic Assignment of Methyl-NMR Spectra of Supramolecular Machines Using Graph Theory.

Pritišanac I, Degiacomi MT, Alderson TR, Carneiro MG, Ab E, Siegal G, Baldwin AJ. Pritišanac I, et al. Among authors: siegal g. J Am Chem Soc. 2017 Jul 19;139(28):9523-9533. doi: 10.1021/jacs.6b11358. Epub 2017 Jul 10. J Am Chem Soc. 2017. PMID: 28691806

5

Target immobilization as a strategy for NMR-based fragment screening: comparison of TINS, STD, and SPR for fragment hit identification.

Kobayashi M, Retra K, Figaroa F, Hollander JG, Ab E, Heetebrij RJ, Irth H, Siegal G. Kobayashi M, et al. Among authors: siegal g. J Biomol Screen. 2010 Sep;15(8):978-89. doi: 10.1177/1087057110375614. J Biomol Screen. 2010. PMID: 20817886

6

NMR in target driven drug discovery: why not?

Keiffer S, Carneiro MG, Hollander J, Kobayashi M, Pogoryelev D, Ab E, Theisgen S, Müller G, Siegal G. Keiffer S, et al. Among authors: siegal g. J Biomol NMR. 2020 Nov;74(10-11):521-529. doi: 10.1007/s10858-020-00343-9. Epub 2020 Sep 8. J Biomol NMR. 2020. PMID: 32901320 Free PMC article.

7

Small-molecule binding sites on proteins established by paramagnetic NMR spectroscopy.

Guan JY, Keizers PH, Liu WM, Löhr F, Skinner SP, Heeneman EA, Schwalbe H, Ubbink M, Siegal G. Guan JY, et al. Among authors: siegal g. J Am Chem Soc. 2013 Apr 17;135(15):5859-68. doi: 10.1021/ja401323m. Epub 2013 Apr 5. J Am Chem Soc. 2013. PMID: 23509882

8

Interrogating the Essential Bacterial Cell Division Protein FtsQ with Fragments Using Target Immobilized NMR Screening (TINS).

Glas M, Ab E, Hollander J, Siegal G, Luirink J, de Esch I. Glas M, et al. Among authors: siegal g. Int J Mol Sci. 2019 Jul 27;20(15):3684. doi: 10.3390/ijms20153684. Int J Mol Sci. 2019. PMID: 31357624 Free PMC article.

9

Biomolecular NMR: recent advances in liquids, solids and screening.

Siegal G, van Duynhoven J, Baldus M. Siegal G, et al. Curr Opin Chem Biol. 1999 Oct;3(5):530-6. doi: 10.1016/s1367-5931(99)00004-6. Curr Opin Chem Biol. 1999. PMID: 10508666 Review.

10

Perspectives on NMR in drug discovery: a technique comes of age.

Pellecchia M, Bertini I, Cowburn D, Dalvit C, Giralt E, Jahnke W, James TL, Homans SW, Kessler H, Luchinat C, Meyer B, Oschkinat H, Peng J, Schwalbe H, Siegal G. Pellecchia M, et al. Among authors: siegal g. Nat Rev Drug Discov. 2008 Sep;7(9):738-45. doi: 10.1038/nrd2606. Nat Rev Drug Discov. 2008. PMID: 19172689 Free PMC article. Review.

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