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Strikingly conserved gene expression changes of polyamine regulating enzymes among various forms of acute and chronic kidney injury.
Sieckmann T, Schley G, Ögel N, Kelterborn S, Boivin FJ, Fähling M, Ashraf MI, Reichel M, Vigolo E, Hartner A, Lichtenberger FB, Breiderhoff T, Knauf F, Rosenberger C, Aigner F, Schmidt-Ott K, Scholz H, Kirschner KM. Sieckmann T, et al. Kidney Int. 2023 Jul;104(1):90-107. doi: 10.1016/j.kint.2023.04.005. Epub 2023 Apr 28. Kidney Int. 2023. PMID: 37121432
Genetic Variants in ARHGEF6 Cause Congenital Anomalies of the Kidneys and Urinary Tract in Humans, Mice, and Frogs.
Klämbt V, Buerger F, Wang C, Naert T, Richter K, Nauth T, Weiss AC, Sieckmann T, Lai E, Connaughton DM, Seltzsam S, Mann N, Majmundar AJ, Wu CW, Onuchic-Whitford AC, Shril S, Schneider S, Schierbaum L, Dai R, Bekheirnia MR, Joosten M, Shlomovitz O, Vivante A, Banne E, Mane S, Lifton RP, Kirschner KM, Kispert A, Rosenberger G, Fischer KD, Lienkamp SS, Zegers MMP, Hildebrandt F. Klämbt V, et al. Among authors: sieckmann t. J Am Soc Nephrol. 2023 Feb 1;34(2):273-290. doi: 10.1681/ASN.2022010050. Epub 2023 Nov 22. J Am Soc Nephrol. 2023. PMID: 36414417 Free PMC article.
WT1 regulates HOXB9 gene expression in a bidirectional way.
Schmidt V, Sieckmann T, Kirschner KM, Scholz H. Schmidt V, et al. Among authors: sieckmann t. Biochim Biophys Acta Gene Regul Mech. 2021 Nov-Dec;1864(11-12):194764. doi: 10.1016/j.bbagrm.2021.194764. Epub 2021 Sep 8. Biochim Biophys Acta Gene Regul Mech. 2021. PMID: 34508900
Polyamines, metabolites and metabolomics.
Sieckmann T, Kirschner KM. Sieckmann T, et al. Acta Physiol (Oxf). 2020 Jul;229(3):e13480. doi: 10.1111/apha.13480. Epub 2020 May 10. Acta Physiol (Oxf). 2020. PMID: 32330357 No abstract available.