Sieber A - Search Results

1

Mitogen-activated protein kinase activity drives cell trajectories in colorectal cancer.

Uhlitz F, Bischoff P, Peidli S, Sieber A, Trinks A, Lüthen M, Obermayer B, Blanc E, Ruchiy Y, Sell T, Mamlouk S, Arsie R, Wei TT, Klotz-Noack K, Schwarz RF, Sawitzki B, Kamphues C, Beule D, Landthaler M, Sers C, Horst D, Blüthgen N, Morkel M. Uhlitz F, et al. Among authors: sieber a. EMBO Mol Med. 2021 Oct 7;13(10):e14123. doi: 10.15252/emmm.202114123. Epub 2021 Aug 19. EMBO Mol Med. 2021. PMID: 34409732 Free PMC article.

2

Strong negative feedback from Erk to Raf confers robustness to MAPK signalling.

Fritsche-Guenther R, Witzel F, Sieber A, Herr R, Schmidt N, Braun S, Brummer T, Sers C, Blüthgen N. Fritsche-Guenther R, et al. Among authors: sieber a. Mol Syst Biol. 2011 May 24;7:489. doi: 10.1038/msb.2011.27. Mol Syst Biol. 2011. PMID: 21613978 Free PMC article.

3

Network quantification of EGFR signaling unveils potential for targeted combination therapy.

Klinger B, Sieber A, Fritsche-Guenther R, Witzel F, Berry L, Schumacher D, Yan Y, Durek P, Merchant M, Schäfer R, Sers C, Blüthgen N. Klinger B, et al. Among authors: sieber a. Mol Syst Biol. 2013;9:673. doi: 10.1038/msb.2013.29. Mol Syst Biol. 2013. PMID: 23752269 Free PMC article.

4

The two active X chromosomes in female ESCs block exit from the pluripotent state by modulating the ESC signaling network.

Schulz EG, Meisig J, Nakamura T, Okamoto I, Sieber A, Picard C, Borensztein M, Saitou M, Blüthgen N, Heard E. Schulz EG, et al. Among authors: sieber a. Cell Stem Cell. 2014 Feb 6;14(2):203-16. doi: 10.1016/j.stem.2013.11.022. Cell Stem Cell. 2014. PMID: 24506884 Free article.

5

Analysis of impedance-based cellular growth assays.

Witzel F, Fritsche-Guenther R, Lehmann N, Sieber A, Blüthgen N. Witzel F, et al. Among authors: sieber a. Bioinformatics. 2015 Aug 15;31(16):2705-12. doi: 10.1093/bioinformatics/btv216. Epub 2015 Apr 21. Bioinformatics. 2015. PMID: 25900918

6

Drug Resistance Mechanisms in Colorectal Cancer Dissected with Cell Type-Specific Dynamic Logic Models.

Eduati F, Doldàn-Martelli V, Klinger B, Cokelaer T, Sieber A, Kogera F, Dorel M, Garnett MJ, Blüthgen N, Saez-Rodriguez J. Eduati F, et al. Among authors: sieber a. Cancer Res. 2017 Jun 15;77(12):3364-3375. doi: 10.1158/0008-5472.CAN-17-0078. Epub 2017 Apr 5. Cancer Res. 2017. PMID: 28381545 Free PMC article.

7

An immediate-late gene expression module decodes ERK signal duration.

Uhlitz F, Sieber A, Wyler E, Fritsche-Guenther R, Meisig J, Landthaler M, Klinger B, Blüthgen N. Uhlitz F, et al. Among authors: sieber a. Mol Syst Biol. 2017 May 3;13(5):928. doi: 10.15252/msb.20177554. Mol Syst Biol. 2017. PMID: 28468958 Free PMC article.

8

An immediate-late gene expression module decodes ERK signal duration.

Uhlitz F, Sieber A, Wyler E, Fritsche-Guenther R, Meisig J, Landthaler M, Klinger B, Blüthgen N. Uhlitz F, et al. Among authors: sieber a. Mol Syst Biol. 2017 Sep 25;13(9):944. doi: 10.15252/msb.20177986. Mol Syst Biol. 2017. PMID: 28947433 Free PMC article.

9

Perturbation-response genes reveal signaling footprints in cancer gene expression.

Schubert M, Klinger B, Klünemann M, Sieber A, Uhlitz F, Sauer S, Garnett MJ, Blüthgen N, Saez-Rodriguez J. Schubert M, et al. Among authors: sieber a. Nat Commun. 2018 Jan 2;9(1):20. doi: 10.1038/s41467-017-02391-6. Nat Commun. 2018. PMID: 29295995 Free PMC article.

10

Modelling signalling networks from perturbation data.

Dorel M, Klinger B, Gross T, Sieber A, Prahallad A, Bosdriesz E, Wessels LFA, Blüthgen N. Dorel M, et al. Among authors: sieber a. Bioinformatics. 2018 Dec 1;34(23):4079-4086. doi: 10.1093/bioinformatics/bty473. Bioinformatics. 2018. PMID: 29931053

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