Sidders B - Search Results

1

Ion channels as therapeutic targets: a drug discovery perspective.

Bagal SK, Brown AD, Cox PJ, Omoto K, Owen RM, Pryde DC, Sidders B, Skerratt SE, Stevens EB, Storer RI, Swain NA. Bagal SK, et al. Among authors: sidders b. J Med Chem. 2013 Feb 14;56(3):593-624. doi: 10.1021/jm3011433. Epub 2012 Nov 29. J Med Chem. 2013. PMID: 23121096 Review.

2

Selection, optimization, and pharmacokinetic properties of a novel, potent antiviral locked nucleic acid-based antisense oligomer targeting hepatitis C virus internal ribosome entry site.

Laxton C, Brady K, Moschos S, Turnpenny P, Rawal J, Pryde DC, Sidders B, Corbau R, Pickford C, Murray EJ. Laxton C, et al. Among authors: sidders b. Antimicrob Agents Chemother. 2011 Jul;55(7):3105-14. doi: 10.1128/AAC.00222-11. Epub 2011 Apr 18. Antimicrob Agents Chemother. 2011. PMID: 21502629 Free PMC article.

3

Precompetitive activity to address the biological data needs of drug discovery.

Sidders B, Brockel C, Gutteridge A, Harland L, Jansen PG, McEwen R, Michalovich D, Seidel H, Weiss B, Williams-Jones B, Woodwark M. Sidders B, et al. Nat Rev Drug Discov. 2014 Feb;13(2):83-4. doi: 10.1038/nrd4230. Nat Rev Drug Discov. 2014. PMID: 24481293 No abstract available.

4

Network-Based Drug Discovery: Coupling Network Pharmacology with Phenotypic Screening for Neuronal Excitability.

Sidders B, Karlsson A, Kitching L, Torella R, Karila P, Phelan A. Sidders B, et al. J Mol Biol. 2018 Sep 14;430(18 Pt A):3005-3015. doi: 10.1016/j.jmb.2018.07.016. Epub 2018 Jul 18. J Mol Biol. 2018. PMID: 30030026

5

HDAC inhibitors attenuate the development of hypersensitivity in models of neuropathic pain.

Denk F, Huang W, Sidders B, Bithell A, Crow M, Grist J, Sharma S, Ziemek D, Rice ASC, Buckley NJ, McMahon SB. Denk F, et al. Among authors: sidders b. Pain. 2013 Sep;154(9):1668-1679. doi: 10.1016/j.pain.2013.05.021. Epub 2013 May 18. Pain. 2013. PMID: 23693161 Free PMC article.

6

Molecular causes of transcriptional response: a Bayesian prior knowledge approach.

Zarringhalam K, Enayetallah A, Gutteridge A, Sidders B, Ziemek D. Zarringhalam K, et al. Among authors: sidders b. Bioinformatics. 2013 Dec 15;29(24):3167-73. doi: 10.1093/bioinformatics/btt557. Epub 2013 Sep 26. Bioinformatics. 2013. PMID: 24078682 Free PMC article.

7

A FOXM1 Dependent Mesenchymal-Epithelial Transition in Retinal Pigment Epithelium Cells.

Choudhary P, Dodsworth BT, Sidders B, Gutteridge A, Michaelides C, Duckworth JK, Whiting PJ, Benn CL. Choudhary P, et al. Among authors: sidders b. PLoS One. 2015 Jun 29;10(6):e0130379. doi: 10.1371/journal.pone.0130379. eCollection 2015. PLoS One. 2015. PMID: 26121260 Free PMC article.

8

Deep Sequencing Insights in Therapeutic shRNA Processing and siRNA Target Cleavage Precision.

Denise H, Moschos SA, Sidders B, Burden F, Perkins H, Carter N, Stroud T, Kennedy M, Fancy SA, Lapthorn C, Lavender H, Kinloch R, Suhy D, Corbau R. Denise H, et al. Among authors: sidders b. Mol Ther Nucleic Acids. 2014 Feb 4;3(2):e145. doi: 10.1038/mtna.2013.73. Mol Ther Nucleic Acids. 2014. PMID: 24496437 Free PMC article.

9

Causal reasoning on biological networks: interpreting transcriptional changes.

Chindelevitch L, Ziemek D, Enayetallah A, Randhawa R, Sidders B, Brockel C, Huang ES. Chindelevitch L, et al. Among authors: sidders b. Bioinformatics. 2012 Apr 15;28(8):1114-21. doi: 10.1093/bioinformatics/bts090. Epub 2012 Feb 21. Bioinformatics. 2012. PMID: 22355083

10

Interpreting transcriptional changes using causal graphs: new methods and their practical utility on public networks.

Fakhry CT, Choudhary P, Gutteridge A, Sidders B, Chen P, Ziemek D, Zarringhalam K. Fakhry CT, et al. Among authors: sidders b. BMC Bioinformatics. 2016 Aug 24;17(1):318. doi: 10.1186/s12859-016-1181-8. BMC Bioinformatics. 2016. PMID: 27553489 Free PMC article.

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