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Metabolic activation of tachysterol3 to biologically active hydroxyderivatives that act on VDR, AhR, LXRs, and PPARγ receptors.
Slominski AT, Kim TK, Slominski RM, Song Y, Janjetovic Z, Podgorska E, Reddy SB, Song Y, Raman C, Tang EKY, Fabisiak A, Brzeminski P, Sicinski RR, Atigadda V, Jetten AM, Holick MF, Tuckey RC. Slominski AT, et al. Among authors: sicinski rr. FASEB J. 2022 Aug;36(8):e22451. doi: 10.1096/fj.202200578R. FASEB J. 2022. PMID: 35838947 Free PMC article.
Synthesis of 19-norcalcitriol analogs with elongated side chain.
Brzeminski P, Fabisiak A, Sektas K, Berkowska K, Marcinkowska E, Sicinski RR. Brzeminski P, et al. Among authors: sicinski rr. J Steroid Biochem Mol Biol. 2018 Mar;177:231-234. doi: 10.1016/j.jsbmb.2017.08.008. Epub 2017 Aug 18. J Steroid Biochem Mol Biol. 2018. PMID: 28823515
Chemical synthesis, biological activities and action on nuclear receptors of 20S(OH)D3, 20S,25(OH)2D3, 20S,23S(OH)2D3 and 20S,23R(OH)2D3.
Brzeminski P, Fabisiak A, Slominski RM, Kim TK, Janjetovic Z, Podgorska E, Song Y, Saleem M, Reddy SB, Qayyum S, Song Y, Tuckey RC, Atigadda V, Jetten AM, Sicinski RR, Raman C, Slominski AT. Brzeminski P, et al. Among authors: sicinski rr. Bioorg Chem. 2022 Apr;121:105660. doi: 10.1016/j.bioorg.2022.105660. Epub 2022 Feb 8. Bioorg Chem. 2022. PMID: 35168121 Free PMC article.
59 results