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Small Molecule KRAS Agonist for Mutant KRAS Cancer Therapy.
Xu K, Park D, Magis AT, Zhang J, Zhou W, Sica GL, Ramalingam SS, Curran WJ, Deng X. Xu K, et al. Among authors: sica gl. Mol Cancer. 2019 Apr 10;18(1):85. doi: 10.1186/s12943-019-1012-4. Mol Cancer. 2019. PMID: 30971271 Free PMC article.
Novel small-molecule inhibitors of Bcl-XL to treat lung cancer.
Park D, Magis AT, Li R, Owonikoko TK, Sica GL, Sun SY, Ramalingam SS, Khuri FR, Curran WJ, Deng X. Park D, et al. Among authors: sica gl. Cancer Res. 2013 Sep 1;73(17):5485-96. doi: 10.1158/0008-5472.CAN-12-2272. Epub 2013 Jul 3. Cancer Res. 2013. PMID: 23824742 Free PMC article.
Poly (ADP) ribose polymerase enzyme inhibitor, veliparib, potentiates chemotherapy and radiation in vitro and in vivo in small cell lung cancer.
Owonikoko TK, Zhang G, Deng X, Rossi MR, Switchenko JM, Doho GH, Chen Z, Kim S, Strychor S, Christner SM, Beumer J, Li C, Yue P, Chen A, Sica GL, Ramalingam SS, Kowalski J, Khuri FR, Sun SY. Owonikoko TK, et al. Among authors: sica gl. Cancer Med. 2014 Dec;3(6):1579-94. doi: 10.1002/cam4.317. Epub 2014 Aug 13. Cancer Med. 2014. PMID: 25124282 Free PMC article.
Small-molecule Bax agonists for cancer therapy.
Xin M, Li R, Xie M, Park D, Owonikoko TK, Sica GL, Corsino PE, Zhou J, Ding C, White MA, Magis AT, Ramalingam SS, Curran WJ, Khuri FR, Deng X. Xin M, et al. Among authors: sica gl. Nat Commun. 2014 Sep 17;5:4935. doi: 10.1038/ncomms5935. Nat Commun. 2014. PMID: 25230299 Free PMC article.
Small-Molecule Bcl2 BH4 Antagonist for Lung Cancer Therapy.
Han B, Park D, Li R, Xie M, Owonikoko TK, Zhang G, Sica GL, Ding C, Zhou J, Magis AT, Chen ZG, Shin DM, Ramalingam SS, Khuri FR, Curran WJ, Deng X. Han B, et al. Among authors: sica gl. Cancer Cell. 2015 Jun 8;27(6):852-63. doi: 10.1016/j.ccell.2015.04.010. Epub 2015 May 21. Cancer Cell. 2015. PMID: 26004684 Free PMC article.
Modulation of Bax and mTOR for Cancer Therapeutics.
Li R, Ding C, Zhang J, Xie M, Park D, Ding Y, Chen G, Zhang G, Gilbert-Ross M, Zhou W, Marcus AI, Sun SY, Chen ZG, Sica GL, Ramalingam SS, Magis AT, Fu H, Khuri FR, Curran WJ, Owonikoko TK, Shin DM, Zhou J, Deng X. Li R, et al. Among authors: sica gl. Cancer Res. 2017 Jun 1;77(11):3001-3012. doi: 10.1158/0008-5472.CAN-16-2356. Epub 2017 Apr 5. Cancer Res. 2017. PMID: 28381544 Free PMC article.
Targeting Mcl-1 enhances DNA replication stress sensitivity to cancer therapy.
Chen G, Magis AT, Xu K, Park D, Yu DS, Owonikoko TK, Sica GL, Satola SW, Ramalingam SS, Curran WJ, Doetsch PW, Deng X. Chen G, et al. Among authors: sica gl. J Clin Invest. 2018 Jan 2;128(1):500-516. doi: 10.1172/JCI92742. Epub 2017 Dec 11. J Clin Invest. 2018. PMID: 29227281 Free PMC article.
111 results