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ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling.
Schmidt S, Schumacher N, Schwarz J, Tangermann S, Kenner L, Schlederer M, Sibilia M, Linder M, Altendorf-Hofmann A, Knösel T, Gruber ES, Oberhuber G, Bolik J, Rehman A, Sinha A, Lokau J, Arnold P, Cabron AS, Zunke F, Becker-Pauly C, Preaudet A, Nguyen P, Huynh J, Afshar-Sterle S, Chand AL, Westermann J, Dempsey PJ, Garbers C, Schmidt-Arras D, Rosenstiel P, Putoczki T, Ernst M, Rose-John S. Schmidt S, et al. Among authors: sibilia m. J Exp Med. 2018 Apr 2;215(4):1205-1225. doi: 10.1084/jem.20171696. Epub 2018 Feb 22. J Exp Med. 2018. PMID: 29472497 Free PMC article.
EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patients.
Srivatsa S, Paul MC, Cardone C, Holcmann M, Amberg N, Pathria P, Diamanti MA, Linder M, Timelthaler G, Dienes HP, Kenner L, Wrba F, Prager GW, Rose-John S, Eferl R, Liguori G, Botti G, Martinelli E, Greten FR, Ciardiello F, Sibilia M. Srivatsa S, et al. Among authors: sibilia m. Gastroenterology. 2017 Jul;153(1):178-190.e10. doi: 10.1053/j.gastro.2017.03.053. Epub 2017 Apr 9. Gastroenterology. 2017. PMID: 28400195 Free PMC article.
EGFR is required for FOS-dependent bone tumor development via RSK2/CREB signaling.
Linder M, Glitzner E, Srivatsa S, Bakiri L, Matsuoka K, Shahrouzi P, Dumanic M, Novoszel P, Mohr T, Langer O, Wanek T, Mitterhauser M, Wagner EF, Sibilia M. Linder M, et al. Among authors: sibilia m. EMBO Mol Med. 2018 Nov;10(11):e9408. doi: 10.15252/emmm.201809408. EMBO Mol Med. 2018. PMID: 30361264 Free PMC article.
IDO1+ Paneth cells promote immune escape of colorectal cancer.
Pflügler S, Svinka J, Scharf I, Crncec I, Filipits M, Charoentong P, Tschurtschenthaler M, Kenner L, Awad M, Stift J, Schernthanner M, Bischl R, Herndler-Brandstetter D, Glitzner E, Moll HP, Casanova E, Timelthaler G, Sibilia M, Gnant M, Lax S, Thaler J, Müller M, Strobl B, Mohr T, Kaser A, Trajanoski Z, Heller G, Eferl R. Pflügler S, et al. Among authors: sibilia m. Commun Biol. 2020 May 22;3(1):252. doi: 10.1038/s42003-020-0989-y. Commun Biol. 2020. PMID: 32444775 Free PMC article.
Wnt signaling and Loxl2 promote aggressive osteosarcoma.
Matsuoka K, Bakiri L, Wolff LI, Linder M, Mikels-Vigdal A, Patiño-García A, Lecanda F, Hartmann C, Sibilia M, Wagner EF. Matsuoka K, et al. Among authors: sibilia m. Cell Res. 2020 Oct;30(10):885-901. doi: 10.1038/s41422-020-0370-1. Epub 2020 Jul 20. Cell Res. 2020. PMID: 32686768 Free PMC article.
Psoriatic skin inflammation is promoted by c-Jun/AP-1-dependent CCL2 and IL-23 expression in dendritic cells.
Novoszel P, Holcmann M, Stulnig G, De Sa Fernandes C, Zyulina V, Borek I, Linder M, Bogusch A, Drobits B, Bauer T, Tam-Amersdorfer C, Brunner PM, Stary G, Bakiri L, Wagner EF, Strobl H, Sibilia M. Novoszel P, et al. Among authors: sibilia m. EMBO Mol Med. 2021 Apr 9;13(4):e12409. doi: 10.15252/emmm.202012409. Epub 2021 Mar 16. EMBO Mol Med. 2021. PMID: 33724710 Free PMC article.
DNA hypomethylation leads to cGAS-induced autoinflammation in the epidermis.
Beck MA, Fischer H, Grabner LM, Groffics T, Winter M, Tangermann S, Meischel T, Zaussinger-Haas B, Wagner P, Fischer C, Folie C, Arand J, Schöfer C, Ramsahoye B, Lagger S, Machat G, Eisenwort G, Schneider S, Podhornik A, Kothmayer M, Reichart U, Glösmann M, Tamir I, Mildner M, Sheibani-Tezerji R, Kenner L, Petzelbauer P, Egger G, Sibilia M, Ablasser A, Seiser C. Beck MA, et al. Among authors: sibilia m. EMBO J. 2021 Nov 15;40(22):e108234. doi: 10.15252/embj.2021108234. Epub 2021 Sep 29. EMBO J. 2021. PMID: 34586646 Free PMC article.
Tyk2 is a tumor suppressor in colorectal cancer.
Moritsch S, Mödl B, Scharf I, Janker L, Zwolanek D, Timelthaler G, Casanova E, Sibilia M, Mohr T, Kenner L, Herndler-Brandstetter D, Gerner C, Müller M, Strobl B, Eferl R. Moritsch S, et al. Among authors: sibilia m. Oncoimmunology. 2022 Sep 26;11(1):2127271. doi: 10.1080/2162402X.2022.2127271. eCollection 2022. Oncoimmunology. 2022. PMID: 36185806 Free PMC article.
136 results