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Loss of the Par-1b/MARK2 polarity kinase leads to increased metabolic rate, decreased adiposity, and insulin hypersensitivity in vivo.
Hurov JB, Huang M, White LS, Lennerz J, Choi CS, Cho YR, Kim HJ, Prior JL, Piwnica-Worms D, Cantley LC, Kim JK, Shulman GI, Piwnica-Worms H. Hurov JB, et al. Among authors: shulman gi. Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5680-5. doi: 10.1073/pnas.0701179104. Epub 2007 Mar 19. Proc Natl Acad Sci U S A. 2007. PMID: 17372192 Free PMC article.
Mechanism of insulin resistance in A-ZIP/F-1 fatless mice.
Kim JK, Gavrilova O, Chen Y, Reitman ML, Shulman GI. Kim JK, et al. Among authors: shulman gi. J Biol Chem. 2000 Mar 24;275(12):8456-60. doi: 10.1074/jbc.275.12.8456. J Biol Chem. 2000. PMID: 10722680 Free article.
Assessment of mitochondrial energy coupling in vivo by 13C/31P NMR.
Jucker BM, Dufour S, Ren J, Cao X, Previs SF, Underhill B, Cadman KS, Shulman GI. Jucker BM, et al. Among authors: shulman gi. Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6880-4. doi: 10.1073/pnas.120131997. Proc Natl Acad Sci U S A. 2000. PMID: 10823916 Free PMC article.
Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice.
Klaman LD, Boss O, Peroni OD, Kim JK, Martino JL, Zabolotny JM, Moghal N, Lubkin M, Kim YB, Sharpe AH, Stricker-Krongrad A, Shulman GI, Neel BG, Kahn BB. Klaman LD, et al. Among authors: shulman gi. Mol Cell Biol. 2000 Aug;20(15):5479-89. doi: 10.1128/MCB.20.15.5479-5489.2000. Mol Cell Biol. 2000. PMID: 10891488 Free PMC article.
Syntaxin 4 heterozygous knockout mice develop muscle insulin resistance.
Yang C, Coker KJ, Kim JK, Mora S, Thurmond DC, Davis AC, Yang B, Williamson RA, Shulman GI, Pessin JE. Yang C, et al. Among authors: shulman gi. J Clin Invest. 2001 May;107(10):1311-8. doi: 10.1172/JCI12274. J Clin Invest. 2001. PMID: 11375421 Free PMC article.
589 results