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5-methylcytosine (m5C) RNA modification controls the innate immune response to virus infection by regulating type I interferons.
Zhang Y, Zhang LS, Dai Q, Chen P, Lu M, Kairis EL, Murugaiah V, Xu J, Shukla RK, Liang X, Zou Z, Cormet-Boyaka E, Qiu J, Peeples ME, Sharma A, He C, Li J. Zhang Y, et al. Among authors: shukla rk. Proc Natl Acad Sci U S A. 2022 Oct 18;119(42):e2123338119. doi: 10.1073/pnas.2123338119. Epub 2022 Oct 14. Proc Natl Acad Sci U S A. 2022. PMID: 36240321 Free PMC article.
Inhibition of elastase enhances the adjuvanticity of alum and promotes anti-SARS-CoV-2 systemic and mucosal immunity.
Kim E, Attia Z, Woodfint RM, Zeng C, Kim SH, Steiner HE, Shukla RK, Liyanage NPM, Ghimire S, Li J, Renukaradhya GJ, Satoskar AR, Amer AO, Liu SL, Cormet-Boyaka E, Boyaka PN. Kim E, et al. Among authors: shukla rk. Proc Natl Acad Sci U S A. 2021 Aug 24;118(34):e2102435118. doi: 10.1073/pnas.2102435118. Proc Natl Acad Sci U S A. 2021. PMID: 34353890 Free PMC article.
Pseudomonas aeruginosa pulmonary infection results in S100A8/A9-dependent cardiac dysfunction.
Kumar N, Pestrak MJ, Wu Q, Ahumada OS, Dellos-Nolan S, Saljoughian N, Shukla RK, Mitchem CF, Nagareddy PR, Ganesan LP, William LP, Wozniak DJ, Rajaram MVS. Kumar N, et al. Among authors: shukla rk. PLoS Pathog. 2023 Aug 25;19(8):e1011573. doi: 10.1371/journal.ppat.1011573. eCollection 2023 Aug. PLoS Pathog. 2023. PMID: 37624851 Free PMC article.
189 results