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Cellular Model of p21-Induced Senescence.
Shtutman M, Chang BD, Schools GP, Broude EV. Shtutman M, et al. Methods Mol Biol. 2017;1534:31-39. doi: 10.1007/978-1-4939-6670-7_3. Methods Mol Biol. 2017. PMID: 27812865 Free PMC article.
CDK8/19 Mediator kinases potentiate induction of transcription by NFκB.
Chen M, Liang J, Ji H, Yang Z, Altilia S, Hu B, Schronce A, McDermott MSJ, Schools GP, Lim CU, Oliver D, Shtutman MS, Lu T, Stark GR, Porter DC, Broude EV, Roninson IB. Chen M, et al. Among authors: shtutman ms. Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10208-10213. doi: 10.1073/pnas.1710467114. Epub 2017 Aug 30. Proc Natl Acad Sci U S A. 2017. PMID: 28855340 Free PMC article.
Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in vitro and in vivo.
Ding X, Sharko AC, McDermott MSJ, Schools GP, Chumanevich A, Ji H, Li J, Zhang L, Mack ZT, Sikirzhytski V, Shtutman M, Ivers L, O'Donovan N, Crown J, Győrffy B, Chen M, Roninson IB, Broude EV. Ding X, et al. Among authors: shtutman m. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2201073119. doi: 10.1073/pnas.2201073119. Epub 2022 Aug 1. Proc Natl Acad Sci U S A. 2022. PMID: 35914167 Free PMC article.
Identifying Cancers Impacted by CDK8/19.
Roninson IB, Győrffy B, Mack ZT, Shtil AA, Shtutman MS, Chen M, Broude EV. Roninson IB, et al. Among authors: shtutman ms. Cells. 2019 Aug 3;8(8):821. doi: 10.3390/cells8080821. Cells. 2019. PMID: 31382571 Free PMC article.
Inhibition of the Dead Box RNA Helicase 3 Prevents HIV-1 Tat and Cocaine-Induced Neurotoxicity by Targeting Microglia Activation.
Aksenova M, Sybrandt J, Cui B, Sikirzhytski V, Ji H, Odhiambo D, Lucius MD, Turner JR, Broude E, Peña E, Lizarraga S, Zhu J, Safro I, Wyatt MD, Shtutman M. Aksenova M, et al. Among authors: shtutman m. J Neuroimmune Pharmacol. 2020 Jun;15(2):209-223. doi: 10.1007/s11481-019-09885-8. Epub 2019 Dec 4. J Neuroimmune Pharmacol. 2020. PMID: 31802418 Free PMC article.
Depletion of COPI in cancer cells: the role of reactive oxygen species in the induction of lipid accumulation, noncanonical lipophagy and apoptosis.
Gasparian A, Aksenova M, Oliver D, Levina E, Doran R, Lucius M, Piroli G, Oleinik N, Ogretmen B, Mythreye K, Frizzell N, Broude E, Wyatt MD, Shtutman M. Gasparian A, et al. Among authors: shtutman m. Mol Biol Cell. 2022 Dec 1;33(14):ar135. doi: 10.1091/mbc.E21-08-0420. Epub 2022 Oct 12. Mol Biol Cell. 2022. PMID: 36222847 Free PMC article.
82 results