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An Alkynylpyrimidine-Based Covalent Inhibitor That Targets a Unique Cysteine in NF-κB-Inducing Kinase.
J Med Chem. 2021 Jul 22;64(14):10001-10018. doi: 10.1021/acs.jmedchem.0c01249. Epub 2021 Jul 2.
J Med Chem. 2021.
PMID: 34212719
Antibody-Proteolysis Targeting Chimera Conjugate Enables Selective Degradation of Receptor-Interacting Serine/Threonine-Protein Kinase 2 in HER2+ Cell Lines.
Chan K, Sathyamurthi PS, Queisser MA, Mullin M, Shrives H, Coe DM, Burley GA.
Chan K, et al.
Bioconjug Chem. 2023 Nov 15;34(11):2049-2054. doi: 10.1021/acs.bioconjchem.3c00366. Epub 2023 Nov 2.
Bioconjug Chem. 2023.
PMID: 37917829
Free PMC article.
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Synthesis of C2 Substituted Benzothiophenes via an Interrupted Pummerer/[3,3]-Sigmatropic/1,2-Migration Cascade of Benzothiophene S-Oxides.
He Z, Shrives HJ, Fernández-Salas JA, Abengózar A, Neufeld J, Yang K, Pulis AP, Procter DJ.
He Z, et al. Among authors: shrives hj.
Angew Chem Int Ed Engl. 2018 May 14;57(20):5759-5764. doi: 10.1002/anie.201801982. Epub 2018 Apr 10.
Angew Chem Int Ed Engl. 2018.
PMID: 29528177
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Regioselective synthesis of C3 alkylated and arylated benzothiophenes.
Shrives HJ, Fernández-Salas JA, Hedtke C, Pulis AP, Procter DJ.
Shrives HJ, et al.
Nat Commun. 2017 Mar 20;8:14801. doi: 10.1038/ncomms14801.
Nat Commun. 2017.
PMID: 28317882
Free PMC article.
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Sulfoxide-Directed Metal-Free ortho-Propargylation of Aromatics and Heteroaromatics.
Eberhart AJ, Shrives HJ, Álvarez E, Carrër A, Zhang Y, Procter DJ.
Eberhart AJ, et al. Among authors: shrives hj.
Chemistry. 2015 May 11;21(20):7313. doi: 10.1002/chem.201501070. Epub 2015 Apr 1.
Chemistry. 2015.
PMID: 25832900
No abstract available.
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Sulfoxide-Directed Metal-Free ortho-Propargylation of Aromatics and Heteroaromatics.
Eberhart AJ, Shrives HJ, Álvarez E, Carrër A, Zhang Y, Procter DJ.
Eberhart AJ, et al. Among authors: shrives hj.
Chemistry. 2015 May 11;21(20):7428-34. doi: 10.1002/chem.201406424. Epub 2015 Mar 6.
Chemistry. 2015.
PMID: 25752800
Free PMC article.
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