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Page 1
Tumor Suppressor Par-4 Regulates Complement Factor C3 and Obesity.
Araujo N, Sledziona J, Noothi SK, Burikhanov R, Hebbar N, Ganguly S, Shrestha-Bhattarai T, Zhu B, Katz WS, Zhang Y, Taylor BS, Liu J, Chen L, Weiss HL, He D, Wang C, Morris AJ, Cassis LA, Nikolova-Karakashian M, Nagareddy PR, Melander O, Evers BM, Kern PA, Rangnekar VM. Araujo N, et al. Among authors: shrestha bhattarai t. Front Oncol. 2022 Mar 29;12:860446. doi: 10.3389/fonc.2022.860446. eCollection 2022. Front Oncol. 2022. PMID: 35425699 Free PMC article.
Novel mechanism of apoptosis resistance in cancer mediated by extracellular PAR-4.
Burikhanov R, Shrestha-Bhattarai T, Qiu S, Shukla N, Hebbar N, Lele SM, Horbinski C, Rangnekar VM. Burikhanov R, et al. Among authors: shrestha bhattarai t. Cancer Res. 2013 Jan 15;73(2):1011-9. doi: 10.1158/0008-5472.CAN-12-3212. Epub 2012 Nov 30. Cancer Res. 2013. PMID: 23204231 Free PMC article.
Par(-4)oxysm in breast cancer.
Shrestha-Bhattarai T, Hebbar N, Rangnekar VM. Shrestha-Bhattarai T, et al. Cancer Cell. 2013 Jul 8;24(1):3-5. doi: 10.1016/j.ccr.2013.06.010. Cancer Cell. 2013. PMID: 23845436 Free PMC article.
Paracrine apoptotic effect of p53 mediated by tumor suppressor Par-4.
Burikhanov R, Shrestha-Bhattarai T, Hebbar N, Qiu S, Zhao Y, Zambetti GP, Rangnekar VM. Burikhanov R, et al. Among authors: shrestha bhattarai t. Cell Rep. 2014 Jan 30;6(2):271-7. doi: 10.1016/j.celrep.2013.12.020. Epub 2014 Jan 9. Cell Rep. 2014. PMID: 24412360 Free PMC article.
Cancer-selective apoptosis by tumor suppressor par-4.
Hebbar N, Shrestha-Bhattarai T, Rangnekar VM. Hebbar N, et al. Among authors: shrestha bhattarai t. Adv Exp Med Biol. 2014;818:155-66. doi: 10.1007/978-1-4471-6458-6_7. Adv Exp Med Biol. 2014. PMID: 25001535 Review.
Par-4 prevents breast cancer recurrence.
Hebbar N, Shrestha-Bhattarai T, Rangnekar VM. Hebbar N, et al. Among authors: shrestha bhattarai t. Breast Cancer Res. 2013;15(5):314. doi: 10.1186/bcr3562. Breast Cancer Res. 2013. PMID: 24164776 Free PMC article.
AKT mutant allele-specific activation dictates pharmacologic sensitivities.
Shrestha Bhattarai T, Shamu T, Gorelick AN, Chang MT, Chakravarty D, Gavrila EI, Donoghue MTA, Gao J, Patel S, Gao SP, Reynolds MH, Phillips SM, Soumerai T, Abida W, Hyman DM, Schram AM, Solit DB, Smyth LM, Taylor BS. Shrestha Bhattarai T, et al. Nat Commun. 2022 Apr 19;13(1):2111. doi: 10.1038/s41467-022-29638-1. Nat Commun. 2022. PMID: 35440569 Free PMC article. Clinical Trial.
AKT1 E17K Inhibits Cancer Cell Migration by Abrogating β-Catenin Signaling.
Gao SP, Kiliti AJ, Zhang K, Vasani N, Mao N, Jordan E, Wise HC, Shrestha Bhattarai T, Hu W, Dorso M, Rodrigues JA, Kim K, Hanrahan AJ, Razavi P, Carver B, Chandarlapaty S, Reis-Filho JS, Taylor BS, Solit DB. Gao SP, et al. Among authors: shrestha bhattarai t. Mol Cancer Res. 2021 Apr;19(4):573-584. doi: 10.1158/1541-7786.MCR-20-0623. Epub 2020 Dec 10. Mol Cancer Res. 2021. PMID: 33303690 Free PMC article.