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Page 1
Cytoplasmic chromatin triggers inflammation in senescence and cancer.
Dou Z, Ghosh K, Vizioli MG, Zhu J, Sen P, Wangensteen KJ, Simithy J, Lan Y, Lin Y, Zhou Z, Capell BC, Xu C, Xu M, Kieckhaefer JE, Jiang T, Shoshkes-Carmel M, Tanim KMAA, Barber GN, Seykora JT, Millar SE, Kaestner KH, Garcia BA, Adams PD, Berger SL. Dou Z, et al. Among authors: shoshkes carmel m. Nature. 2017 Oct 19;550(7676):402-406. doi: 10.1038/nature24050. Epub 2017 Oct 4. Nature. 2017. PMID: 28976970 Free PMC article.
Foxl1-expressing mesenchymal cells constitute the intestinal stem cell niche.
Aoki R, Shoshkes-Carmel M, Gao N, Shin S, May CL, Golson ML, Zahm AM, Ray M, Wiser CL, Wright CV, Kaestner KH. Aoki R, et al. Among authors: shoshkes carmel m. Cell Mol Gastroenterol Hepatol. 2016 Feb 1;2(2):175-188. doi: 10.1016/j.jcmgh.2015.12.004. Cell Mol Gastroenterol Hepatol. 2016. PMID: 26949732 Free PMC article.
Combined hepatocellular-cholangiocarcinoma derives from liver progenitor cells and depends on senescence and IL-6 trans-signaling.
Rosenberg N, Van Haele M, Lanton T, Brashi N, Bromberg Z, Adler H, Giladi H, Peled A, Goldenberg DS, Axelrod JH, Simerzin A, Chai C, Paldor M, Markezana A, Yaish D, Shemulian Z, Gross D, Barnoy S, Gefen M, Amran O, Claerhout S, Fernández-Vaquero M, García-Beccaria M, Heide D, Shoshkes-Carmel M, Schmidt Arras D, Elgavish S, Nevo Y, Benyamini H, Tirnitz-Parker JEE, Sanchez A, Herrera B, Safadi R, Kaestner KH, Rose-John S, Roskams T, Heikenwalder M, Galun E. Rosenberg N, et al. Among authors: shoshkes carmel m. J Hepatol. 2022 Dec;77(6):1631-1641. doi: 10.1016/j.jhep.2022.07.029. Epub 2022 Aug 18. J Hepatol. 2022. PMID: 35988690
TET2 and TET3 loss disrupts small intestine differentiation and homeostasis.
Ansari I, Solé-Boldo L, Ridnik M, Gutekunst J, Gilliam O, Korshko M, Liwinski T, Jickeli B, Weinberg-Corem N, Shoshkes-Carmel M, Pikarsky E, Elinav E, Lyko F, Bergman Y. Ansari I, et al. Among authors: shoshkes carmel m. Nat Commun. 2023 Jul 6;14(1):4005. doi: 10.1038/s41467-023-39512-3. Nat Commun. 2023. PMID: 37414790 Free PMC article.
Lgr5+ telocytes are a signaling source at the intestinal villus tip.
Bahar Halpern K, Massalha H, Zwick RK, Moor AE, Castillo-Azofeifa D, Rozenberg M, Farack L, Egozi A, Miller DR, Averbukh I, Harnik Y, Weinberg-Corem N, de Sauvage FJ, Amit I, Klein OD, Shoshkes-Carmel M, Itzkovitz S. Bahar Halpern K, et al. Among authors: shoshkes carmel m. Nat Commun. 2020 Apr 22;11(1):1936. doi: 10.1038/s41467-020-15714-x. Nat Commun. 2020. PMID: 32321913 Free PMC article.
Telocytes in the Luminal GI Tract.
Shoshkes-Carmel M. Shoshkes-Carmel M. Cell Mol Gastroenterol Hepatol. 2024;17(5):697-701. doi: 10.1016/j.jcmgh.2024.02.002. Epub 2024 Feb 9. Cell Mol Gastroenterol Hepatol. 2024. PMID: 38342300 Free PMC article. Review.