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The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments.
Zhang JG, Czabotar PE, Policheni AN, Caminschi I, Wan SS, Kitsoulis S, Tullett KM, Robin AY, Brammananth R, van Delft MF, Lu J, O'Reilly LA, Josefsson EC, Kile BT, Chin WJ, Mintern JD, Olshina MA, Wong W, Baum J, Wright MD, Huang DC, Mohandas N, Coppel RL, Colman PM, Nicola NA, Shortman K, Lahoud MH. Zhang JG, et al. Among authors: shortman k. Immunity. 2012 Apr 20;36(4):646-57. doi: 10.1016/j.immuni.2012.03.009. Epub 2012 Apr 5. Immunity. 2012. PMID: 22483802 Free article.
The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement.
Caminschi I, Proietto AI, Ahmet F, Kitsoulis S, Shin Teh J, Lo JC, Rizzitelli A, Wu L, Vremec D, van Dommelen SL, Campbell IK, Maraskovsky E, Braley H, Davey GM, Mottram P, van de Velde N, Jensen K, Lew AM, Wright MD, Heath WR, Shortman K, Lahoud MH. Caminschi I, et al. Among authors: shortman k. Blood. 2008 Oct 15;112(8):3264-73. doi: 10.1182/blood-2008-05-155176. Epub 2008 Jul 30. Blood. 2008. PMID: 18669894 Free PMC article.
Enhancing immune responses by targeting antigen to DC.
Caminschi I, Lahoud MH, Shortman K. Caminschi I, et al. Among authors: shortman k. Eur J Immunol. 2009 Apr;39(4):931-8. doi: 10.1002/eji.200839035. Eur J Immunol. 2009. PMID: 19197943 Free article.
Targeting antigen to mouse dendritic cells via Clec9A induces potent CD4 T cell responses biased toward a follicular helper phenotype.
Lahoud MH, Ahmet F, Kitsoulis S, Wan SS, Vremec D, Lee CN, Phipson B, Shi W, Smyth GK, Lew AM, Kato Y, Mueller SN, Davey GM, Heath WR, Shortman K, Caminschi I. Lahoud MH, et al. Among authors: shortman k. J Immunol. 2011 Jul 15;187(2):842-50. doi: 10.4049/jimmunol.1101176. Epub 2011 Jun 15. J Immunol. 2011. PMID: 21677141
Evolution of B cell responses to Clec9A-targeted antigen.
Park HY, Light A, Lahoud MH, Caminschi I, Tarlinton DM, Shortman K. Park HY, et al. Among authors: shortman k. J Immunol. 2013 Nov 15;191(10):4919-25. doi: 10.4049/jimmunol.1301947. Epub 2013 Oct 11. J Immunol. 2013. PMID: 24123689
RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cells.
Tullett KM, Tan PS, Park HY, Schittenhelm RB, Michael N, Li R, Policheni AN, Gruber E, Huang C, Fulcher AJ, Danne JC, Czabotar PE, Wakim LM, Mintern JD, Ramm G, Radford KJ, Caminschi I, O'Keeffe M, Villadangos JA, Wright MD, Blewitt ME, Heath WR, Shortman K, Purcell AW, Nicola NA, Zhang JG, Lahoud MH. Tullett KM, et al. Among authors: shortman k. Elife. 2020 Dec 2;9:e63452. doi: 10.7554/eLife.63452. Elife. 2020. PMID: 33264090 Free PMC article.
316 results