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Crif1 deficiency reduces adipose OXPHOS capacity and triggers inflammation and insulin resistance in mice.
Ryu MJ, Kim SJ, Kim YK, Choi MJ, Tadi S, Lee MH, Lee SE, Chung HK, Jung SB, Kim HJ, Jo YS, Kim KS, Lee SH, Kim JM, Kweon GR, Park KC, Lee JU, Kong YY, Lee CH, Chung J, Shong M. Ryu MJ, et al. Among authors: shong m. PLoS Genet. 2013;9(3):e1003356. doi: 10.1371/journal.pgen.1003356. Epub 2013 Mar 14. PLoS Genet. 2013. PMID: 23516375 Free PMC article.
SIRT2 regulates tumour hypoxia response by promoting HIF-1α hydroxylation.
Seo KS, Park JH, Heo JY, Jing K, Han J, Min KN, Kim C, Koh GY, Lim K, Kang GY, Uee Lee J, Yim YH, Shong M, Kwak TH, Kweon GR. Seo KS, et al. Among authors: shong m. Oncogene. 2015 Mar 12;34(11):1354-62. doi: 10.1038/onc.2014.76. Epub 2014 Mar 31. Oncogene. 2015. PMID: 24681946
Reduced oxidative capacity in macrophages results in systemic insulin resistance.
Jung SB, Choi MJ, Ryu D, Yi HS, Lee SE, Chang JY, Chung HK, Kim YK, Kang SG, Lee JH, Kim KS, Kim HJ, Kim CS, Lee CH, Williams RW, Kim H, Lee HK, Auwerx J, Shong M. Jung SB, et al. Among authors: shong m. Nat Commun. 2018 Apr 19;9(1):1551. doi: 10.1038/s41467-018-03998-z. Nat Commun. 2018. PMID: 29674655 Free PMC article.
Endothelial-specific Crif1 deletion induces BBB maturation and disruption via the alteration of actin dynamics by impaired mitochondrial respiration.
Lee MJ, Jang Y, Han J, Kim SJ, Ju X, Lee YL, Cui J, Zhu J, Ryu MJ, Choi SY, Chung W, Heo C, Yi HS, Kim HJ, Huh YH, Chung SK, Shong M, Kweon GR, Heo JY. Lee MJ, et al. Among authors: shong m. J Cereb Blood Flow Metab. 2020 Jul;40(7):1546-1561. doi: 10.1177/0271678X19900030. Epub 2020 Jan 27. J Cereb Blood Flow Metab. 2020. PMID: 31987007 Free PMC article.
216 results