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Pyrimidine inhibitors synergize with nucleoside analogues to block SARS-CoV-2.
Schultz DC, Johnson RM, Ayyanathan K, Miller J, Whig K, Kamalia B, Dittmar M, Weston S, Hammond HL, Dillen C, Ardanuy J, Taylor L, Lee JS, Li M, Lee E, Shoffler C, Petucci C, Constant S, Ferrer M, Thaiss CA, Frieman MB, Cherry S. Schultz DC, et al. Among authors: shoffler c. Nature. 2022 Apr;604(7904):134-140. doi: 10.1038/s41586-022-04482-x. Epub 2022 Feb 7. Nature. 2022. PMID: 35130559 Free PMC article.
A subpopulation of lipogenic brown adipocytes drives thermogenic memory.
Lundgren P, Sharma PV, Dohnalová L, Coleman K, Uhr GT, Kircher S, Litichevskiy L, Bahnsen K, Descamps HC, Demetriadou C, Chan J, Chellappa K, Cox TO, Heyman Y, Pather SR, Shoffler C, Petucci C, Shalem O, Raj A, Baur JA, Snyder NW, Wellen KE, Levy M, Seale P, Li M, Thaiss CA. Lundgren P, et al. Among authors: shoffler c. Nat Metab. 2023 Oct;5(10):1691-1705. doi: 10.1038/s42255-023-00893-w. Epub 2023 Oct 2. Nat Metab. 2023. PMID: 37783943