Shoemaker CB - Search Results

1

Engineered Escherichia coli for the in situ secretion of therapeutic nanobodies in the gut.

Lynch JP, González-Prieto C, Reeves AZ, Bae S, Powale U, Godbole NP, Tremblay JM, Schmidt FI, Ploegh HL, Kansra V, Glickman JN, Leong JM, Shoemaker CB, Garrett WS, Lesser CF. Lynch JP, et al. Among authors: shoemaker cb. Cell Host Microbe. 2023 Apr 12;31(4):634-649.e8. doi: 10.1016/j.chom.2023.03.007. Epub 2023 Mar 31. Cell Host Microbe. 2023. PMID: 37003258 Free PMC article.

2

Co-administration of an effector antibody enhances the half-life and therapeutic potential of RNA-encoded nanobodies.

Thran M, Pönisch M, Danz H, Horscroft N, Ichtchenko K, Tzipori S, Shoemaker CB. Thran M, et al. Among authors: shoemaker cb. Sci Rep. 2023 Sep 5;13(1):14632. doi: 10.1038/s41598-023-41092-7. Sci Rep. 2023. PMID: 37670025 Free PMC article.

3

Single-domain antibodies reveal unique borrelicidal epitopes on the Lyme disease vaccine antigen, outer surface protein A (OspA).

Vance DJ, Basir S, Piazza CL, Willsey GG, Haque HME, Tremblay JM, Rudolph MJ, Muriuki B, Cavacini L, Weis DD, Shoemaker CB, Mantis NJ. Vance DJ, et al. Among authors: shoemaker cb. Infect Immun. 2024 Apr 9;92(4):e0008424. doi: 10.1128/iai.00084-24. Epub 2024 Mar 12. Infect Immun. 2024. PMID: 38470113 Free PMC article.

4

Anti-schistosomal immunity to core xylose/fucose in N-glycans.

Prasanphanich NS, Leon K, Secor WE, Shoemaker CB, Heimburg-Molinaro J, Cummings RD. Prasanphanich NS, et al. Among authors: shoemaker cb. Front Mol Biosci. 2023 Apr 4;10:1142620. doi: 10.3389/fmolb.2023.1142620. eCollection 2023. Front Mol Biosci. 2023. PMID: 37081851 Free PMC article.

5

Yeast Display Enables Identification of Covalent Single-Domain Antibodies against Botulinum Neurotoxin Light Chain A.

Alcala-Torano R, Islam M, Cika J, Lam KH, Jin R, Ichtchenko K, Shoemaker CB, Van Deventer JA. Alcala-Torano R, et al. Among authors: shoemaker cb. ACS Chem Biol. 2022 Dec 16;17(12):3435-3449. doi: 10.1021/acschembio.2c00574. Epub 2022 Dec 2. ACS Chem Biol. 2022. PMID: 36459441 Free PMC article.

6

Enteric pharmacokinetics of monomeric and multimeric camelid nanobody single-domain antibodies.

Debatis M, Danz H, Tremblay JM, Gaspie K, Kudej RK, Vigdorovich V, Sather N, Jaskiewicz JJ, Tzipori S, Shoemaker CB. Debatis M, et al. Among authors: shoemaker cb. PLoS One. 2023 Nov 27;18(11):e0291937. doi: 10.1371/journal.pone.0291937. eCollection 2023. PLoS One. 2023. PMID: 38011121 Free PMC article.

7

Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2.

Liu Z, Lee PG, Krez N, Lam KH, Liu H, Przykopanski A, Chen P, Yao G, Zhang S, Tremblay JM, Perry K, Shoemaker CB, Rummel A, Dong M, Jin R. Liu Z, et al. Among authors: shoemaker cb. Nat Commun. 2023 Apr 24;14(1):2338. doi: 10.1038/s41467-023-37860-8. Nat Commun. 2023. PMID: 37095076 Free PMC article.

8

Single domain antibodies against enteric pathogen virulence factors are active as curli fiber fusions on probiotic E. coli Nissle 1917.

Gelfat I, Aqeel Y, Tremblay JM, Jaskiewicz JJ, Shrestha A, Lee JN, Hu S, Qian X, Magoun L, Sheoran A, Bedenice D, Giem C, Manjula-Basavanna A, Pulsifer AR, Tu HX, Li X, Minus ML, Osburne MS, Tzipori S, Shoemaker CB, Leong JM, Joshi NS. Gelfat I, et al. Among authors: shoemaker cb. PLoS Pathog. 2022 Sep 15;18(9):e1010713. doi: 10.1371/journal.ppat.1010713. eCollection 2022 Sep. PLoS Pathog. 2022. PMID: 36107831 Free PMC article.

9

Intramuscular delivery of formulated RNA encoding six linked nanobodies is highly protective for exposures to three Botulinum neurotoxin serotypes.

Mukherjee J, Ondeck CA, Tremblay JM, Archer J, Debatis M, Foss A, Awata J, Erasmus JH, McNutt PM, Shoemaker CB. Mukherjee J, et al. Among authors: shoemaker cb. Sci Rep. 2022 Jul 8;12(1):11664. doi: 10.1038/s41598-022-15876-2. Sci Rep. 2022. PMID: 35803998 Free PMC article.

10

Probing the structure and function of the protease domain of botulinum neurotoxins using single-domain antibodies.

Lam KH, Tremblay JM, Perry K, Ichtchenko K, Shoemaker CB, Jin R. Lam KH, et al. Among authors: shoemaker cb. PLoS Pathog. 2022 Jan 6;18(1):e1010169. doi: 10.1371/journal.ppat.1010169. eCollection 2022 Jan. PLoS Pathog. 2022. PMID: 34990480 Free PMC article.

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