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Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1.
Tsai PY, Lee MS, Jadhav U, Naqvi I, Madha S, Adler A, Mistry M, Naumenko S, Lewis CA, Hitchcock DS, Roberts FR, DelNero P, Hank T, Honselmann KC, Morales Oyarvide V, Mino-Kenudson M, Clish CB, Shivdasani RA, Kalaany NY. Tsai PY, et al. Among authors: shivdasani ra. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2003014118. doi: 10.1073/pnas.2003014118. Proc Natl Acad Sci U S A. 2021. PMID: 33653947 Free PMC article.
TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions.
Verzi MP, Hatzis P, Sulahian R, Philips J, Schuijers J, Shin H, Freed E, Lynch JP, Dang DT, Brown M, Clevers H, Liu XS, Shivdasani RA. Verzi MP, et al. Among authors: shivdasani ra. Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15157-62. doi: 10.1073/pnas.1003822107. Epub 2010 Aug 9. Proc Natl Acad Sci U S A. 2010. PMID: 20696899 Free PMC article.
Natural Selection, Crypt Fitness, and Pol III Dependency in the Intestine.
Jadhav U, Shivdasani RA. Jadhav U, et al. Among authors: shivdasani ra. Cell Mol Gastroenterol Hepatol. 2016 Sep 26;2(6):714-715. doi: 10.1016/j.jcmgh.2016.09.006. eCollection 2016 Nov. Cell Mol Gastroenterol Hepatol. 2016. PMID: 28174745 Free PMC article. No abstract available.
RORα-expressing T regulatory cells restrain allergic skin inflammation.
Malhotra N, Leyva-Castillo JM, Jadhav U, Barreiro O, Kam C, O'Neill NK, Meylan F, Chambon P, von Andrian UH, Siegel RM, Wang EC, Shivdasani R, Geha RS. Malhotra N, et al. Sci Immunol. 2018 Mar 2;3(21):eaao6923. doi: 10.1126/sciimmunol.aao6923. Sci Immunol. 2018. PMID: 29500225 Free PMC article.
192 results