Shirihai OS - Search Results

1

Parkin regulates adiposity by coordinating mitophagy with mitochondrial biogenesis in white adipocytes.

Moore TM, Cheng L, Wolf DM, Ngo J, Segawa M, Zhu X, Strumwasser AR, Cao Y, Clifford BL, Ma A, Scumpia P, Shirihai OS, Vallim TQA, Laakso M, Lusis AJ, Hevener AL, Zhou Z. Moore TM, et al. Among authors: shirihai os. Nat Commun. 2022 Nov 4;13(1):6661. doi: 10.1038/s41467-022-34468-2. Nat Commun. 2022. PMID: 36333379 Free PMC article.

2

Estrogen receptor α protects pancreatic β-cells from apoptosis by preserving mitochondrial function and suppressing endoplasmic reticulum stress.

Zhou Z, Ribas V, Rajbhandari P, Drew BG, Moore TM, Fluitt AH, Reddish BR, Whitney KA, Georgia S, Vergnes L, Reue K, Liesa M, Shirihai O, van der Bliek AM, Chi NW, Mahata SK, Tiano JP, Hewitt SC, Tontonoz P, Korach KS, Mauvais-Jarvis F, Hevener AL. Zhou Z, et al. J Biol Chem. 2018 Mar 30;293(13):4735-4751. doi: 10.1074/jbc.M117.805069. Epub 2018 Jan 29. J Biol Chem. 2018. PMID: 29378845 Free PMC article.

3

Individual islet respirometry reveals functional diversity within the islet population of mice and human donors.

Taddeo EP, Stiles L, Sereda S, Ritou E, Wolf DM, Abdullah M, Swanson Z, Wilhelm J, Bellin M, McDonald P, Caradonna K, Neilson A, Liesa M, Shirihai OS. Taddeo EP, et al. Among authors: shirihai os. Mol Metab. 2018 Oct;16:150-159. doi: 10.1016/j.molmet.2018.07.003. Epub 2018 Jul 25. Mol Metab. 2018. PMID: 30098928 Free PMC article.

4

Initial B Cell Activation Induces Metabolic Reprogramming and Mitochondrial Remodeling.

Waters LR, Ahsan FM, Wolf DM, Shirihai O, Teitell MA. Waters LR, et al. iScience. 2018 Jul 27;5:99-109. doi: 10.1016/j.isci.2018.07.005. Epub 2018 Jul 10. iScience. 2018. PMID: 30240649 Free PMC article.

5

The impact of exercise on mitochondrial dynamics and the role of Drp1 in exercise performance and training adaptations in skeletal muscle.

Moore TM, Zhou Z, Cohn W, Norheim F, Lin AJ, Kalajian N, Strumwasser AR, Cory K, Whitney K, Ho T, Ho T, Lee JL, Rucker DH, Shirihai O, van der Bliek AM, Whitelegge JP, Seldin MM, Lusis AJ, Lee S, Drevon CA, Mahata SK, Turcotte LP, Hevener AL. Moore TM, et al. Mol Metab. 2019 Mar;21:51-67. doi: 10.1016/j.molmet.2018.11.012. Epub 2018 Dec 4. Mol Metab. 2019. PMID: 30591411 Free PMC article.

6

IAPP toxicity activates HIF1α/PFKFB3 signaling delaying β-cell loss at the expense of β-cell function.

Montemurro C, Nomoto H, Pei L, Parekh VS, Vongbunyong KE, Vadrevu S, Gurlo T, Butler AE, Subramaniam R, Ritou E, Shirihai OS, Satin LS, Butler PC, Tudzarova S. Montemurro C, et al. Among authors: shirihai os. Nat Commun. 2019 Jun 18;10(1):2679. doi: 10.1038/s41467-019-10444-1. Nat Commun. 2019. PMID: 31213603 Free PMC article.

7

Individual cristae within the same mitochondrion display different membrane potentials and are functionally independent.

Wolf DM, Segawa M, Kondadi AK, Anand R, Bailey ST, Reichert AS, van der Bliek AM, Shackelford DB, Liesa M, Shirihai OS. Wolf DM, et al. Among authors: shirihai os. EMBO J. 2019 Nov 15;38(22):e101056. doi: 10.15252/embj.2018101056. Epub 2019 Oct 14. EMBO J. 2019. PMID: 31609012 Free PMC article.

8

MitoTimer-based high-content screen identifies two chemically-related benzothiophene derivatives that enhance basal mitophagy.

Cerqueira FM, Kozer N, Petcherski A, Baranovski BM, Wolf D, Assali EA, Roth Y, Gazit R, Barr H, Lewis EC, Las G, Shirihai OS. Cerqueira FM, et al. Among authors: shirihai os. Biochem J. 2020 Jan 31;477(2):461-475. doi: 10.1042/BCJ20190616. Biochem J. 2020. PMID: 32003437

9

Cristae undergo continuous cycles of membrane remodelling in a MICOS-dependent manner.

Kondadi AK, Anand R, Hänsch S, Urbach J, Zobel T, Wolf DM, Segawa M, Liesa M, Shirihai OS, Weidtkamp-Peters S, Reichert AS. Kondadi AK, et al. Among authors: shirihai os. EMBO Rep. 2020 Mar 4;21(3):e49776. doi: 10.15252/embr.201949776. Epub 2020 Feb 18. EMBO Rep. 2020. PMID: 32067344 Free PMC article.

10

Method for live-cell super-resolution imaging of mitochondrial cristae and quantification of submitochondrial membrane potentials.

Wolf DM, Segawa M, Shirihai OS, Liesa M. Wolf DM, et al. Among authors: shirihai os. Methods Cell Biol. 2020;155:545-555. doi: 10.1016/bs.mcb.2019.12.006. Epub 2020 Mar 4. Methods Cell Biol. 2020. PMID: 32183976 Free PMC article.

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